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抑制剂/受体激动剂
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Deuterated
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Pyrimidines
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产品名字索引 D
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产品名字索引 D
丹参素
(Catalog# : 17021315, Cas# :
76822-21-4
)
丹参素,一种中药制剂,具有潜在的抗肿瘤和抗血管生成作用。
2,3-dimethyl-2,5-cyclohexadiene-1,4 dione
(Catalog# : 17011908, Cas# :
526-86-3
)
2,5-Cyclohexadiene-1,4-dione,2,3-dimethyl-
4,5-Dihydro-2-(Methylthio)-1H-iMidazole-1-carboxylic Acid Methyl Ester
(Catalog# : 17011907, Cas# :
60546-77-2
)
It is a new drug
Doxapram
(Catalog# : 16122937, Cas# :
309-29-5
)
Doxapram is a respiratory stimulant. Administered intravenously, doxapram stimulates
Dobutamine HCl
(Catalog# : 16122936, Cas# :
34368-04-2
)
Dobutamine is a sympathomimetic drug used in the treatment of heart failure and cardi
DM1-SMe
(Catalog# : 16122935, Cas# :
138148-68-2
)
DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a
DM1-SMCC
(Catalog# : 16122934, Cas# :
1228105-51-8
)
DM1-SMCC is DM1 with a reactive linker SMCC, which can react with antibody to make an
Dimethylenastron
(Catalog# : 16122932, Cas# :
863774-58-7
)
Dimethylenastron is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM). Dimeth
Dihydroethidium
(Catalog# : 16122931, Cas# :
104821-25-2
)
Dihydroethidium, also known as Hydroethidine and PD-MY 003, is a cell-permeable blue
Delamanid (OPC-67683)
(Catalog# : 16122930, Cas# :
681492-22-8
)
Delamanid, also known as OPC-67683, is a drug for the treatment of multi-drug-resista
Defactinib
(Catalog# : 16122929, Cas# :
1073160-26-5
)
Defactinib, also known as VS-6063 and PF04554878, is an orally bioavailable, small-mo
Debio-1347
(Catalog# : 16122928, Cas# :
1265229-25-1
)
Debio-1347, also known as FF284 and CH5183284, is an orally bioavailable inhibitor of
Darinaparsin
(Catalog# : 16122927, Cas# :
69819-86-9
)
Darinaparsin, also know as ZIO-101 is a small-molecule organic arsenical with potenti
Daclatasvir
(Catalog# : 16122926, Cas# :
1009119-64-5
)
Daclatasvir (USAN), also known as BMS-790052 and EBP-883 (trade name Daklinza), is NS
D-64131
(Catalog# : 16122925, Cas# :
74588-78-6
)
D-64131 is a potent and selective tubulin inhibitor. D-64131 inhibits tumor cell prol
Dalbavancin HCl
(Catalog# : 16122808, Cas# :
171500-79-1
)
Dalbavancin is a novel second-generation lipoglycopeptide antibiotic. It belongs to t
Dabrafenib mesylate
(Catalog# : 16122807, Cas# :
1195768-06-9
)
Dabrafenib mesylate, also known as GSK 2118436B, is a potent and orally active B-raf
Dolutegravir Sodium
(Catalog# : 16122764, Cas# :
1051375-19-9
)
Dolutegravir is a HIV integrase inhibitor with IC50 of 2.7 nM.Dolutegravir(S/GSK13495
DCVC
(Catalog# : 6111408, Cas# :
13419-46-0
)
DCVC inhibits pathogen-stimulated TNF- in human extra placental membranes in vitro.
Danirixin
(Catalog# : 16111111, Cas# :
954126-98-8
)
Danirixin is a small molecule, non-peptide, high affinity (IC50 for CXCL8 binding = 1
Defactinib
(Catalog# : 6111019, Cas# :
1345713-71-4
)
Defactinib(VS-6063, PF-04554878)
2,3-dimethoxybenzonitrile
(Catalog# : 6111003, Cas# :
5653-62-3
)
2,3-dimethoxybenzonitrile
10-Deacetyl-7-xylosyl paclitaxel
(Catalog# : 611946, Cas# :
90332-63-1
)
10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacolog
Debio 0932
(Catalog# : 611938, Cas# :
1061318-81-7
)
Debio 0932 ( CUDC-305 ) is a novel heat shock protein 90 (HSP90) inhibitor trong affi
DUBs-IN-3
(Catalog# : 611929, Cas# :
924296-17-3
)
DUBs-IN-3 is a potent deubiquitinase enzyme inhibitor with IC50s of 3.1 uM for USP8;
DUBs-IN-1
(Catalog# : 611928, Cas# :
924296-18-4
)
DUBs-IN-1 is a potent deubiquitinase enzyme inhibitor with IC50s of 18 uM/0.71 uM for
DMAT
(Catalog# : 611913, Cas# :
749234-11-5
)
DMAT is a potent and specific CK2 inhibitor with an IC50 of 0.13 uM.
Dovitinib
(Catalog# : 16071106, Cas# :
405169-16-6
)
Dovitinib, also known as TKI-258 or CHIR-258, is an orally bioavailable FGFR3 inhibit
Dasotraline
(Catalog# : 16071017, Cas# :
675126-05-3
)
Dasotraline, also known as SEP-225,289, is a serotonin-norepinephrine-dopamine reupta
DeBio-1143 (AT-406)
(Catalog# : 16070501, Cas# :
1071992-99-8
)
 DeBio-1143, also known as AT-406, ARRY-334543and SM-406, is an orally bioavaila
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
ECI830
(Catalog# : 26A031, Cas# :
3054692-62-2
)
ECI830是一种实验性的CDK2抑制剂。
GNE-317
(Catalog# : 52282, Cas# :
1394076-92-6
)
GNE-317 is a potent, brain-penetrantPI3Kinhibitor
DPTX-3186
(Catalog# : 26A010, Cas# :
3118994-80-9
)
DPTX3186 是一种口服的小分子凝聚体调节剂 (c-mod),可抑制 β-catenin
Avasopasem manganese (GC-4419; M-40419)
(Catalog# : 25108, Cas# :
435327-40-5
)
Avasopasem manganese, 也称为GC-4419、M 40419和SC-72325A,是超氧化物歧化酶
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Kartogenin ( KGN )
(Catalog# : 52215, Cas# :
4727-31-5
)
Kartogenin(KGN)是一种合成小分子,通过激活smad-4/5通路刺激软骨细
Imisopasem manganese ( M40403; GC4403 )
(Catalog# : 72602, Cas# :
218791-21-0
)
Imisopasem manganese ( M40403; GC4403 ) 是一种稳定的非肽类 MnSOD 类似物,
Apecotrep (BI 764198)
(Catalog# : 26A048, Cas# :
2311863-36-0
)
Apecotrep(BI 764198)是一种潜在的同类首创、口服、选择性的TRPC6抑
Pantothenate kinase-IN-2
(Catalog# : 26A038, Cas# :
902614-04-4
)
Pantothenate kinase-IN-2是一种泛酸激酶抑制剂,对PanK2的IC50值为92 nM,
BH-30643
(Catalog# : 26A047, Cas# :
3062177-59-4
)
BH-30643是一种新型、口服、非共价、大环、突变选择性OMNI-EGFR抑制