Darinaparsin
编号: 16122927
Cas号: 69819-86-9
纯度: 98%
Darinaparsin, also know as ZIO-101 is a small-molecule organic arsenical with potential antineoplastic activity. Although the exact mechanism of action is unclear, darinaparsin, a highly toxic metabolic intermediate of inorganic arsenicals (iAs) that occurs in vivo, appears to generate volatile cytotoxic arsenic compounds when glutathione (GSH) concentrations are low. The arsenic compounds generated from darinaparsin disrupt mitochondrial bioenergetics, producing reactive oxygen species (ROS) and inducing ROS-mediated tumor cell apoptosis; in addition, this agent or its byproducts may initiate cell death by interrupting the G2/M phase of the cell cycle and may exhibit antiangiogenic effects.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Darinaparsin |
|---|---|
| Iupac 化学名称 | Darinaparsin |
| 同义词 | ZIO 101; ZIO101; ZIO-101. Darinaparsin; Zinapar |
| 英文同义词 | ZIO 101; ZIO101; ZIO-101. Darinaparsin; Zinapar |
| 分子式 | C12H22AsN3O6S |
| 分子量 | 411.31 |
| Smile | C[As](C)SC[C@@H](C(=O)NCC(=O)O)NC(=O)CC[C@@H](C(=O)O)N |
| InChiKey | JGDXFQORBMPJGR-YUMQZZPRSA-N |
| InChi | InChI=1S/C12H22AsN3O6S/c1-13(2)23-6-8(11(20)15-5-10(18)19)16-9(17)4-3-7(14)12(21)22/h7-8H,3-6,14H2,1-2H3,(H,15,20)(H,16,17)(H,18,19)(H,21,22)/t7-,8-/m0/s1 |
| Cas号 | 69819-86-9 |
| MDL | MFCD17215931 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
