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DM1-SMe

Catalog No.: 16122935
Cas No.: 138148-68-2
Purity : 98% 
16122935 - DM1-SMe | CAS 138148-68-2

Catalog number : 16122935

CAS number : 138148-68-2

分子式 : C36H50ClN3O10S2 

分子量 : 784.377 

Iupac 化学名称 : DM1-SMe 

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同义词maytansinoid derivative with ADC linker. Maytansine or mertansine or emtansine derivative; N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]maytansine 
英文同义词maytansinoid derivative with ADC linker. Maytansine or mertansine or emtansine derivative; N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]maytansine 
分子式C36H50ClN3O10S2 
分子量784.377 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
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DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group. DM1-SMe can be readily conjugate to the SH group of an antibody to form antibody-drug conjugate (ADC). 

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