Dimethylenastron
编号: 16122932
Cas号: 863774-58-7
纯度: 98%
Dimethylenastron is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM). Dimethylenastron suppresses human pancreatic cancer cell migration and invasion in vitro via allosteric inhibition of mitotic kinesin Eg5. The inhibition of kinesin Eg5 by small molecules such as monastrol is currently evaluated as an approach to develop a novel class of antiproliferative drugs for the treatment of malignant tumours.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Dimethylenastron |
|---|---|
| Iupac 化学名称 | Dimethylenastron |
| 同义词 | N/A |
| 英文同义词 | N/A |
| 分子式 | C16H18N2O2S |
| 分子量 | 302.392 |
| Smile | CC1(CC2=C(C(NC(=S)N2)c3cccc(c3)O)C(=O)C1)C |
| InChiKey | RUOOPLOUUAYNPY-UHFFFAOYSA-N |
| InChi | InChI=1S/C16H18N2O2S/c1-16(2)7-11-13(12(20)8-16)14(18-15(21)17-11)9-4-3-5-10(19)6-9/h3-6,14,19H,7-8H2,1-2H3,(H2,17,18,21) |
| Cas号 | 863774-58-7 |
| MDL | MFCD09264157 |
| 相关CAS号 |
订购信息
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