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D-64131

Catalog No.: 16122925
Cas No.: 74588-78-6
Purity : 98% 
16122925 - D-64131 | CAS 74588-78-6

Catalog number : 16122925

CAS number : 74588-78-6

分子式 : C16H13NO2 

分子量 : 251.285 

Iupac 化学名称 : D-64131 

Smile : COc1ccc2c(c1)cc([nH]2)C(=O)c3ccccc3

InChiKey : ICMIJSRDISNKOC-UHFFFAOYSA-N

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同义词D 64131; D64131 
英文同义词D 64131; D64131 
分子式C16H13NO2 
分子量251.285 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
SmileCOc1ccc2c(c1)cc([nH]2)C(=O)c3ccccc3
InChiKeyICMIJSRDISNKOC-UHFFFAOYSA-N
InChiInChI=1S/C16H13NO2/c1-19-13-7-8-14-12(9-13)10-15(17-14)16(18)11-5-3-2-4-6-11/h2-10,17H,1H3
MDLMFCD04039791
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D-64131 is a potent and selective tubulin inhibitor. D-64131 inhibits tumor cell proliferation in vitro (IC50 = 74 nM). In xenograft experiments with the human amelanoic melanoma MEXF 989, D-64131 was highly active with treatment resulting in a growth delay of 23.4 days at 400 mg/kg. 

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