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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Deuterated
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产品名字索引 A
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产品名字索引 A
AC710
(Catalog# : 80702, Cas# :
1351522-04-7
)
AC710 is a potent, selective PDGFR-family kinases inhibitor with Kd values of 0.6 nM/
4-Amino-3-iodobenzoic acid
(Catalog# : 80311, Cas# :
2122-63-6
)
Coming soon!
ALPHA-BENZYL-4,6-O-BENZYLIDENE-MURAMIC ACID
(Catalog# : 80302, Cas# :
19229-57-3
)
Coming soon
AZD2014(Vistusertib)
(Catalog# : 71804, Cas# :
1009298-59-2
)
AZD2014is a potent (IC50 2.81 nM), selective (inactive against 220 other kinases) inh
AZD9496
(Catalog# : 71802, Cas# :
1639042-08-2
)
1) Sponsor:AstraZeneca2) Phase:Phase 13)AZD9496 is a novel, oral selective oestrogen
Alpelisib(BYL719)
(Catalog# : 62504, Cas# :
1217486-61-7
)
NVP-BYL719 is novel and specific PI3K inhibitor.NVP-BYL719 has displayed promising re
Apitolisib(GDC-0980,RG7422)
(Catalog# : 62503, Cas# :
1032754-93-0
)
Apitolisib(GDC-0980,RG7422) is a dual PI3K/mTOR inhibitor.GDC-0980 was potent across
Atazanavir
(Catalog# : 61005, Cas# :
198904-31-3
)
Atazanavir(BMS-232632) is an highly potent HIV-1 protease inhibitor.
Abexinostat
(Catalog# : 60702, Cas# :
783355-60-2
)
Abexinostat is a novel hydroxamate-based HDACi that showed broad spectrum anticancer
Axitinib
(Catalog# : 52771, Cas# :
319460-85-0
)
Axitinib, also known as AG013736, is an orally bioavailable tyrosine kinase inhibitor
AVL-292
(Catalog# : 52770, Cas# :
1202757-89-8
)
AVL-292 is a covalent, highly selective, orally active small molecule inhibitor of Bt
AT9283
(Catalog# : 52769, Cas# :
896466-04-9
)
AT9283 is a small molecule a multi-targeted inhibitor with IC50s of 4, 1.2, 1.1 and a
AT13387
(Catalog# : 52768, Cas# :
912999-49-6
)
AT13387 is a selective potent Hsp90 inhibitor with IC50 of 18 nM in A375 cells, displ
Asenapine maleate
(Catalog# : 52767, Cas# :
85650-56-2
)
Asenapine maleate(Org 5222 maleate) inhibits adrenergic receptor (1, 2A, 2B, 2C) with
AP26113
(Catalog# : 52766, Cas# :
1197958-12-5
)
AP26113 is a potent and selective active inhibitor of anaplastic lymphoma kinase(ALK)
AM095 free acid
(Catalog# : 52765, Cas# :
1228690-36-5
)
AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 M for re
APY0201
(Catalog# : 52759, Cas# :
1232221-74-7
)
APY0201 is a potent, highly selective, ATP-competitive PIKfyve inhibitor (IC50=5.2 nM
AI-10-49
(Catalog# : 52757, Cas# :
1256094-72-0
)
AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBF-SMM
AEE788
(Catalog# : 52750, Cas# :
497839-62-0
)
AEE788(NVP-AEE 788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM an
Alogliptin Benzoate
(Catalog# : 52741, Cas# :
850649-62-6
)
Alogliptin benzoate(SYR 322) is a potent, selective inhibitor of DPP-4 with IC50 of &
AHAS inhibitor
(Catalog# : 52739, Cas# :
219793-45-0
)
AHAS inhibitor is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug
AZ20
(Catalog# : 52734, Cas# :
1233339-22-4
)
AZ20 is a potent and selective inhibitor of ATR with an IC50 of 5 nM; 8-fold selectiv
Afatinib
(Catalog# : 52719, Cas# :
850140-72-6
)
Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R),
AICAR
(Catalog# : 52702, Cas# :
2627-69-2
)
AICAR (Acadesine), is an AMP-activated protein kinase activator, which is used for th
AMG-319
(Catalog# : 52026, Cas# :
1608125-21-8
)
AMG 319 is an investigational, highly selective, small molecule inhibitor of PI3K tha
AMG-925
(Catalog# : 51614, Cas# :
1401033-86-0
)
AMG-925 is a potent and orally bioavailable dual inhibitor of CDK4 and FLT3, includin
ABT-737
(Catalog# : 52640, Cas# :
852808-04-9
)
ABT-737 is a BH3 mimetic inhibitor ofBcl-xL,Bcl-2andBcl-wwithEC50of 78.7 nM, 30.3 nM
AZD-7762
(Catalog# : 52638, Cas# :
860352-01-8
)
AZD7762 is a potent and selective inhibitor of Chk1 with IC50 of 5 nM; equally potent
AZD1080
(Catalog# : 52626, Cas# :
612487-72-6
)
AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor of GSK3 and GSK
A-674563
(Catalog# : 52617, Cas# :
552325-73-2
)
A-674563 is a potent selective Akt1 inhibitor with an IC50 of 14 nM; also shows inhib
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
Kartogenin ( KGN )
(Catalog# : 52215, Cas# :
4727-31-5
)
Kartogenin(KGN)是一种合成小分子,通过激活smad-4/5通路刺激软骨细
Imisopasem manganese ( M40403; GC4403 )
(Catalog# : 72602, Cas# :
218791-21-0
)
Imisopasem manganese ( M40403; GC4403 ) 是一种稳定的非肽类 MnSOD 类似物,
Apecotrep (BI 764198)
(Catalog# : 26A048, Cas# :
2311863-36-0
)
Apecotrep(BI 764198)是一种潜在的同类首创、口服、选择性的TRPC6抑
Pantothenate kinase-IN-2
(Catalog# : 26A038, Cas# :
902614-04-4
)
Pantothenate kinase-IN-2是一种泛酸激酶抑制剂,对PanK2的IC50值为92 nM,
BH-30643
(Catalog# : 26A047, Cas# :
3062177-59-4
)
BH-30643是一种新型、口服、非共价、大环、突变选择性OMNI-EGFR抑制
Gridegalutamide
(Catalog# : 26A044, Cas# :
2446929-86-6
)
格列德加鲁胺是一种具有口服生物利用度的雄激素受体(AR)降解
BMS-986365 (别名: CC-94676 )
(Catalog# : 25138, Cas# :
2446928-30-7
)
BMS-986365,也称为 CC-94676,是一种口服生物可利用的雄激素受体 (A
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
VAS3947
(Catalog# : 20302, Cas# :
869853-70-3
)
VAS3947是一种低微摩尔浓度的NADPH氧化酶活性的选择性抑制剂,既不