APY0201 is a potent, highly selective, ATP-competitive PIKfyve inhibitor (IC50=5.2 nM) that interrupts the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3,5)P2; a unique small molecular IL-12/23 production inhibitor.
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化学信息
| 名称 | APY0201 |
| 分子式 | C23H23N7O |
| 分子量 | 413.48 |
| InChiKey | |
| InChi | |
| Cas号 | 1232221-74-7 |
| 相关CAS号 | |
| 纯度 | 98% |
| 可溶性 | 10 mM in DMSO |
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| 海关编码 | |
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| Cell study | |
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