AVL-292 is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM; >1400-fold selectivity over the other kinases assayed.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | AVL-292 |
| 分子式 | C22H22FN5O3 |
| 分子量 | 423.44 |
| InChiKey | |
| InChi | |
| Cas号 | 1202757-89-8 |
| 相关CAS号 | |
| 纯度 | 98% |
| 可溶性 | DMSO 80 mg/ml; Water <1 mg/ml |
| 处理方式 | |
| 海关编码 | |
| Targets | |
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | |