武汉永璨生物科技有限公司
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抑制剂/受体激动剂
Angiogenesis
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JAK/STAT
MAPK
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Metabolic Enzyme/Protease
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NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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PROTAC
Antibody-drug Conjugate/ADC Related
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分子砌块
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Anilines
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Bromides
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Deuterated
Fluorides
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
Nuclear Receptor
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Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
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订购信息
联系我们
公司简介
联系我们
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产品名字索引 A
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产品名字索引 A
Alisertib(MLN8237)
(Catalog# : 52587, Cas# :
1028486-01-2
)
Alisertib (MLN8237) is a selective Aurora A inhibitor with IC50 of 1.2 nM; has >20
AMG-208
(Catalog# : 52585, Cas# :
1002304-34-8
)
AMG-208 is a potent small molecular c-Met inhibitor with an IC50 of 9.3 nM.
AZD-5438
(Catalog# : 52577, Cas# :
602306-29-6
)
AZD5438 is a potent inhibitor of CDK1/2/9 with IC50 of 16 nM/6 nM/20 nM. It is less p
AZD1283
(Catalog# : 52573, Cas# :
919351-41-0
)
AZD1283 is a potent antagonist of the P2Y12 receptor with EC50 of 3.0 ug/kg/min, TI &
Apoptosis Activator 2
(Catalog# : 52551, Cas# :
79183-19-0
)
Apoptosis Activator 2 is a potent apoptosis activator; increases procaspase-9 process
AGI-6780
(Catalog# : 52547, Cas# :
1432660-47-3
)
AGI-6780 is the first highly potent and selective small molecule inhibitor of isocitr
AP-III-a4
(Catalog# : 52538, Cas# :
1177827-73-4
)
ENOblock(AP-III-a4) is a novel small molecule which is the first, nonsubstrate analog
AWD 131-138
(Catalog# : 52533, Cas# :
188116-07-6
)
AWD 131-138(Imepitoin) is a new low-affinity partial benzodiazepine receptor agonist
Ampalex
(Catalog# : 52524, Cas# :
154235-83-3
)
Ampalex (Ampakine CX516; CX516; BDP 12) is an ampakine and nootropic that acts as an
AR-A014418
(Catalog# : 52523, Cas# :
487021-52-3
)
AR-A014418 is a selective and effective GSK3 inhibitor with an IC 50 value of 104 +/-
AG 18
(Catalog# : 52504, Cas# :
118409-57-7
)
AG-18(RG-50810; Tyrphostin A23) inhibits EGFR with IC50 of 40 M.
AG-1478
(Catalog# : 52222, Cas# :
153436-53-4
)
AG-1478 (NSC 693255) is a selective EGFR inhibitor with IC50 of 3 nM; almost no activ
Atglistatinc
(Catalog# : 52240, Cas# :
1469924-27-3
)
Atglistatin is a highly potent, selective and competitive inhibitor of adipose trigly
ATB-346
(Catalog# : 52232, Cas# :
1226895-20-0
)
ATB-346 is a novel hydrogen sulphide-releasing derivative of naproxen with markedly r
Afobazole
(Catalog# : 52242, Cas# :
173352-21-1
)
Afobazole (CM346) is an anxiolytic drug; produces anxiolytic and neuroprotective effe
AT7519
(Catalog# : 52314, Cas# :
844442-38-2
)
AT7519 is a multi-CDKinhibitor for CDK1, 2, 4, 6 and 9 withIC50of 10-210 nM. It is le
Aceclofenac
(Catalog# : 51914, Cas# :
89796-99-6
)
Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac.
Alectinib(CH5424802)
(Catalog# : 51907, Cas# :
1256580-46-7
)
Alectinibis a second-generation, orally active, potent and highly selective inhibitor
AZD1152-HQPA
(Catalog# : 51904, Cas# :
722544-51-6
)
Barasertib (AZD1152-HQPA) is a highly selectiveAurora Binhibitor withIC50of 0.37 nM,
AZD6482
(Catalog# : 51603, Cas# :
1173900-33-8
)
AZD6482 is aPI3Kinhibitor withIC50of 10 nM, 8-, 87- and 109-fold more selective to PI
AZD1208
(Catalog# : 51702, Cas# :
1204144-28-4
)
AZD1208 is a potent, highly selective, and orally available Pim kinase inhibitor that
AZ3146
(Catalog# : 51903, Cas# :
1124329-14-1
)
AZ3146 is a selectiveMps1inhibitor withIC50of ~35 nM, contributes to recruitment of C
AT13148
(Catalog# : 51902, Cas# :
1056901-62-2
)
AT13148, a first-in-class multi-AGC kinase inhibitor, against gastric cancer cells. A
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
Kartogenin ( KGN )
(Catalog# : 52215, Cas# :
4727-31-5
)
Kartogenin(KGN)是一种合成小分子,通过激活smad-4/5通路刺激软骨细
Imisopasem manganese ( M40403; GC4403 )
(Catalog# : 72602, Cas# :
218791-21-0
)
Imisopasem manganese ( M40403; GC4403 ) 是一种稳定的非肽类 MnSOD 类似物,
Apecotrep (BI 764198)
(Catalog# : 26A048, Cas# :
2311863-36-0
)
Apecotrep(BI 764198)是一种潜在的同类首创、口服、选择性的TRPC6抑
Pantothenate kinase-IN-2
(Catalog# : 26A038, Cas# :
902614-04-4
)
Pantothenate kinase-IN-2是一种泛酸激酶抑制剂,对PanK2的IC50值为92 nM,
BH-30643
(Catalog# : 26A047, Cas# :
3062177-59-4
)
BH-30643是一种新型、口服、非共价、大环、突变选择性OMNI-EGFR抑制
Gridegalutamide
(Catalog# : 26A044, Cas# :
2446929-86-6
)
格列德加鲁胺是一种具有口服生物利用度的雄激素受体(AR)降解
BMS-986365 (别名: CC-94676 )
(Catalog# : 25138, Cas# :
2446928-30-7
)
BMS-986365,也称为 CC-94676,是一种口服生物可利用的雄激素受体 (A
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
VAS3947
(Catalog# : 20302, Cas# :
869853-70-3
)
VAS3947是一种低微摩尔浓度的NADPH氧化酶活性的选择性抑制剂,既不