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A-674563

Catalog No.: 52617
Cas No.: 552325-73-2
Purity : 98% 
52617 - A-674563 | CAS 552325-73-2

Catalog number : 52617

CAS number : 552325-73-2

分子式 : C22H22N4O 

分子量 : 358.44 

化学名称 : A-674563

Smile : Cc1c2cc(ccc2[nH]n1)c3cc(cnc3)OC[C@H](Cc4ccccc4)N.Cl

InChiKey : HLNHYVLLEFHBJD-FYZYNONXSA-N

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分子式C22H22N4O 
分子量358.44 
纯度98% 
SmileCc1c2cc(ccc2[nH]n1)c3cc(cnc3)OC[C@H](Cc4ccccc4)N.Cl
InChiKeyHLNHYVLLEFHBJD-FYZYNONXSA-N
InChiInChI=1S/C22H22N4O.ClH/c1-15-21-11-17(7-8-22(21)26-25-15)18-10-20(13-24-12-18)27-14-19(23)9-16-5-3-2-4-6-16;/h2-8,10-13,19H,9,14,23H2,1H3,(H,25,26);1H/t19-;/m0./s1
MDLMFCD18711680
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A-674563 is a potent selective Akt1 inhibitor with an IC50 of 14 nM; also shows inhibitory activity against PKA and CDK2 with IC50 of 16 and 46 nM, respectively. 

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