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AMG-319

Catalog No.: 52026
Cas No.: 1608125-21-8
Purity : 98% 
52026 - AMG-319 | CAS 1608125-21-8

Catalog number : 52026

CAS number : 1608125-21-8

分子式 : C21H16FN7 

分子量 : 385.40 

Iupac 化学名称 : (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine 

Smile : C[C@H](NC1=C2N=CNC2=NC=N1)C3=CC4=CC=C(F)C=C4N=C3C5=NC=CC=C5

InChiKey : KWRYMZHCQIOOEB-LBPRGKRZSA-N

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同义词AMG-319; AMG319; AMG 319. 
英文同义词AMG-319; AMG319; AMG 319. 
分子式C21H16FN7 
分子量385.40 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature 
SmileC[C@H](NC1=C2N=CNC2=NC=N1)C3=CC4=CC=C(F)C=C4N=C3C5=NC=CC=C5
InChiKeyKWRYMZHCQIOOEB-LBPRGKRZSA-N
InChiInChI=1S/C21H16FN7/c1-12(28-21-19-20(25-10-24-19)26-11-27-21)15-8-13-5-6-14(22)9-17(13)29-18(15)16-4-2-3-7-23-16/h2-12H,1H3,(H2,24,25,26,27,28)/t12-/m0/s1
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AMG 319 is an investigational, highly selective, small molecule inhibitor of PI3K that blocks B cell proliferation following BCR stimulation both in vitro and in vivo, inhibits basal AKT phosphorylation, and inhibits proliferation in lymphoid tumor cells.

 

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