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AZD9496

Catalog No.: 71802
Cas No.: 1639042-08-2
Purity : 98% 
71802 - AZD9496 | CAS 1639042-08-2

Catalog number : 71802

CAS number : 1639042-08-2

分子式 : C25H25F3N2O2 

分子量 : 442.48 

Iupac 化学名称 : (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic acid 

Smile : O=C(O)/C=C/C1=CC(F)=C([C@H]2N(CC(C)(F)C)[C@H](C)CC3=C2NC4=C3C=CC=C4)C(F)=C1

InChiKey : DFBDRVGWBHBJNR-BBNFHIFMSA-N

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同义词AZD 9496;AZD-9496 
英文同义词AZD 9496;AZD-9496 
分子式C25H25F3N2O2 
分子量442.48 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 6 months-80ºCin solvent 
运输条件Shipped under ambient temperature 
SmileO=C(O)/C=C/C1=CC(F)=C([C@H]2N(CC(C)(F)C)[C@H](C)CC3=C2NC4=C3C=CC=C4)C(F)=C1
InChiKeyDFBDRVGWBHBJNR-BBNFHIFMSA-N
InChiInChI=1S/C25H25F3N2O2/c1-14-10-17-16-6-4-5-7-20(16)29-23(17)24(30(14)13-25(2,3)28)22-18(26)11-15(12-19(22)27)8-9-21(31)32/h4-9,11-12,14,24,29H,10,13H2,1-3H3,(H,31,32)/b9-8+/t14-,24-/m1/s1
Coming soon.

1) Sponsor:AstraZeneca

2) Phase:  Phase 1

3)AZD9496 is a novel, oral selective oestrogen receptor down-regulator (SERD),used for patients with oestrogen receptor positive (ER+) breast cancer. The oral pharmacokinetic properties of AZD9496 will also be presented [Abs3650], demonstrating the significant pre-clinical tumour efficacy that supported its advance into clinical trials.


 

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