Palbociclib(PD-0332991)HCl
Catalog No: 52011
CAS Number: 827022-32-2
Purity: >98% by HPLC
Palbociclib (PD-0332991) HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM respectively. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.
For research use only. We do not sell to patients.
Chemical Information
| Name | Palbociclib(PD-0332991)HCl |
|---|---|
| Iupac Chemical Name | 6-acetyl-8-cyclopentyl-5-methyl-2-(5-(piperazin-1-yl)pyridin-2-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride |
| Synonyms | Palbociclib;PD-0332991 |
| Molecular Formula | C24H29N7O2.HCl |
| Molecular Weight | 483.99 |
| Smile | Cl.C(C)(=O)C1=C(C2=C(N=C(N=C2)NC2=NC=C(C=C2)N2CCNCC2)N(C1=O)C1CCCC1)C |
| InChiKey | STEQOHNDWONVIF-UHFFFAOYSA-N |
| InChi | InChI=1S/C24H29N7O2.ClH/c1-15-19-14-27-24(28-20-8-7-18(13-26-20)30-11-9-25-10-12-30)29-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32;/h7-8,13-14,17,25H,3-6,9-12H2,1-2H3,(H,26,27,28,29);1H |
| CAS Number | 827022-32-2 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | yellow solid |
|---|---|
| Purity | >98% by HPLC |
| Storage | 3 years -20ºCpowder |
| Solubility | 5mg/ml in DMSO,40mg/ml in H2O |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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