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Napabucasin

Catalog No: 16122708
CAS Number: 83280-65-3
Purity: 98% 

Napabucasin is an orally available Stat3 and cancer cell stemness inhibitor.Napabucasin downregulates stemness gene expression driven by Stat3 and cancer stemness properties, and effectively inhibits self-renewal of stemness-high cancer cells with IC50 ranged from 0.291~1.19 M, on inhibition on normal stem cells.  

For research use only. We do not sell to patients.

Chemical Information

NameNapabucasin
Iupac Chemical Name2-Acetylnaphtho[2,3-b]furan-4,9-dione 
SynonymsBBI608; BBI 608; BB-I608; Napabucasin 
Molecular FormulaC14H8O4 
Molecular Weight240.21 
SmileC(C)(=O)C1=CC2=C(O1)C(C1=CC=CC=C1C2=O)=O
InChiKeyDPHUWDIXHNQOSY-UHFFFAOYSA-N
InChiInChI=1S/C14H8O4/c1-7(15)11-6-10-12(16)8-4-2-3-5-9(8)13(17)14(10)18-11/h2-6H,1H3
CAS Number83280-65-3
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16122708 - Napabucasin | CAS 83280-65-3

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