Niraparib HCl
Catalog No: 17030114
CAS Number: 1038915-64-8
Purity: 98%
Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. The PARP family of proteins detect and repair single strand DNA breaks by the base-excision repair (BER) pathway.
For research use only. We do not sell to patients.
Chemical Information
| Name | Niraparib HCl |
|---|---|
| Iupac Chemical Name | Niraparib HCl |
| Synonyms | MK4827; MK 4827; MK4827; Niraparib; Niraparib HCl; Niraparib hydrochloride. |
| Molecular Formula | C19H21ClN4O |
| Molecular Weight | 356.854 |
| Smile | c1cc2cn(nc2c(c1)C(=O)N)c3ccc(cc3)[C@@H]4CCCNC4 |
| InChiKey | PCHKPVIQAHNQLW-CQSZACIVSA-N |
| InChi | InChI=1S/C19H20N4O/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24)/t14-/m1/s1 |
| CAS Number | 1038915-64-8 |
| MDL | MFCD17779309 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
