CO-1686(Rociletinib)
Catalog No: 60701
CAS Number: 1374640-70-6
Purity: 98%
CO-1686(Rociletinib) is an irreversible inhibitor of epidermal growth factor receptor (EGFR).CO-1686(Rociletinib) was used for EGFR-Mutated NonCSmall-Cell Lung Cancer.Rociletinib was active in patients with EGFR-mutated NSCLC associated with the T790M resistance mutation. (Funded by Clovis Oncology; ClinicalTrials.gov number, NCT01526928.)
For research use only. We do not sell to patients.
Chemical Information
| Name | CO-1686(Rociletinib) |
|---|---|
| Iupac Chemical Name | N-(3-((2-((4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl)amino)-5-(trifluorom ethyl)pyrimidin-4-yl)amino)phenyl)acrylamide |
| Synonyms | AVL-301;CNX-4;CO1686;Rociletinib;CO-1686;CO 1686 |
| Molecular Formula | C27H28F3N7O3 |
| Molecular Weight | 555.55 |
| Smile | C(C)(=O)N1CCN(CC1)C1=CC(=C(C=C1)NC1=NC=C(C(=N1)NC=1C=C(C=CC1)NC(C=C)=O)C(F)(F)F)OC |
| InChiKey | HUFOZJXAKZVRNJ-UHFFFAOYSA-N |
| InChi | InChI=1S/C27H28F3N7O3/c1-4-24(39)32-18-6-5-7-19(14-18)33-25-21(27(28,29)30)16-31-26(35-25)34-22-9-8-20(15-23(22)40-3)37-12-10-36(11-13-37)17(2)38/h4-9,14-16H,1,10-13H2,2-3H3,(H,32,39)(H2,31,33,34,35) |
| CAS Number | 1374640-70-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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