CEP-33779
Catalog No: 73105
CAS Number: 1257704-57-6
Purity: 97%
CEP33779 is a selective JAK2 inhibitor with IC50 of 1.8 nM. CEP33779(< 3 M) inhibits phosphorylation of downstream target signal transducer and activator of transcription 5(pSTAT5) of JAK2 in a concentration dependent manner in HEL92 cells.
For research use only. We do not sell to patients.
Chemical Information
| Name | CEP-33779 |
|---|---|
| Iupac Chemical Name | N-(3-(4-methylpiperazin-1-yl)phenyl)-8-(4-(methylsulfonyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine |
| Synonyms | CEP33779; CEP 33779 |
| Molecular Formula | C24H26N6O2S |
| Molecular Weight | 462.57 |
| Smile | CN1CCN(CC1)C=1C=C(C=CC1)NC1=NN2C(C(=CC=C2)C2=CC=C(C=C2)S(=O)(=O)C)=N1 |
| InChiKey | RFZKSQIFOZZIAQ-UHFFFAOYSA-N |
| InChi | InChI=1S/C24H26N6O2S/c1-28-13-15-29(16-14-28)20-6-3-5-19(17-20)25-24-26-23-22(7-4-12-30(23)27-24)18-8-10-21(11-9-18)33(2,31)32/h3-12,17H,13-16H2,1-2H3,(H,25,27) |
| CAS Number | 1257704-57-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 97% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
