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CEP-33779

Catalog No.: 73105
Cas No.: 1257704-57-6
Purity : 97% 
73105 - CEP-33779 | CAS 1257704-57-6

Catalog number : 73105

CAS number : 1257704-57-6

Molecular Formula : C24H26N6O2S 

Molecular Weight : 462.57 

Iupac Chemical Name : N-(3-(4-methylpiperazin-1-yl)phenyl)-8-(4-(methylsulfonyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine 

Smile : CN1CCN(CC1)C=1C=C(C=CC1)NC1=NN2C(C(=CC=C2)C2=CC=C(C=C2)S(=O)(=O)C)=N1

InChiKey : RFZKSQIFOZZIAQ-UHFFFAOYSA-N

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SynonymsCEP33779; CEP 33779 
Molecular FormulaC24H26N6O2S 
Molecular Weight462.57 
AppearanceSolid powder 
Purity97% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileCN1CCN(CC1)C=1C=C(C=CC1)NC1=NN2C(C(=CC=C2)C2=CC=C(C=C2)S(=O)(=O)C)=N1
InChiKeyRFZKSQIFOZZIAQ-UHFFFAOYSA-N
InChiInChI=1S/C24H26N6O2S/c1-28-13-15-29(16-14-28)20-6-3-5-19(17-20)25-24-26-23-22(7-4-12-30(23)27-24)18-8-10-21(11-9-18)33(2,31)32/h3-12,17H,13-16H2,1-2H3,(H,25,27)
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CEP33779 is a selective JAK2 inhibitor with IC50 of 1.8 nM. CEP33779(< 3 M) inhibits phosphorylation of downstream target signal transducer and activator of transcription 5(pSTAT5) of JAK2 in a concentration dependent manner in HEL92 cells. 

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