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CB-839

Catalog No: 16122913
CAS Number: 1439399-58-2
Purity: 98% 

CB-839 an is orally bioavailable inhibitor of glutaminase, with potential antineoplastic activity. Upon oral administration, CB-839 selectively and irreversibly inhibits glutaminase, a mitochondrial enzyme that is essential for the conversion of the amino acid glutamine into glutamate. By blocking glutamine utilization, proliferation in rapidly growing cells is impaired. Glutamine-dependent tumors rely on the conversion of exogenous glutamine into glutamate and glutamate metabolites to both provide energy and generate building blocks for the production of macromolecules, which are needed for cellular growth and survival. 

For research use only. We do not sell to patients.

Chemical Information

NameCB-839
Iupac Chemical NameCB-839 
SynonymsCB839; CB-839; CB 839 
Molecular FormulaC26H24F3N7O3S 
Molecular Weight571.57 
InChiKey
InChi
CAS Number1439399-58-2
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16122913 - CB-839 | CAS 1439399-58-2

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