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AZD7545

Catalog No.: 179136
Cas No.: 252017-04-2
Purity : 98.0%
179136 - AZD7545 | CAS 252017-04-2

Catalog number : 179136

CAS number : 252017-04-2

Molecular Formula : C19H18ClF3N2O5S

Molecular Weight : 478.8672

Iupac Chemical Name : 4-[3-chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]amino]phenyl]sulfonyl-N,N-dimethylbenzamide

Smile : ClC=1C=C(C=CC1NC([C@@](C(F)(F)F)(C)O)=O)S(=O)(=O)C1=CC=C(C(=O)N(C)C)C=C1

InChiKey : DTDZLJHKVNTQGZ-GOSISDBHSA-N

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SynonymsAZD7545; AZD-7545; AZD 7545.
Molecular FormulaC19H18ClF3N2O5S
Molecular Weight478.8672
Appearanceoff-white solid
Purity98.0%
SolubilitySoluble in DMSO
Storage-20 ℃ for 3 years
Shipping ConditionShipped under ambient temperature
SmileClC=1C=C(C=CC1NC([C@@](C(F)(F)F)(C)O)=O)S(=O)(=O)C1=CC=C(C(=O)N(C)C)C=C1
InChiKeyDTDZLJHKVNTQGZ-GOSISDBHSA-N
InChiInChI=1S/C19H18ClF3N2O5S/c1-18(28,19(21,22)23)17(27)24-15-9-8-13(10-14(15)20)31(29,30)12-6-4-11(5-7-12)16(26)25(2)3/h4-10,28H,1-3H3,(H,24,27)/t18-/m1/s1
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AZD7545 is an inhibitor of pyruvate dehydrogenase kinase 2 (PDHK2) (IC50 value of 6.4nM ) for the treatment of type 2 diabetes.

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