APY29
Catalog No: 011108
CAS Number: 1216665-49-4
Purity: 98%
APY29 is an allosteric modulator of IRE1; inhibits IRE1 autophosphorylation (IC50 = 280 nM) and activates IRE1 RNase activity.
For research use only. We do not sell to patients.
Chemical Information
| Name | APY29 |
|---|---|
| Iupac Chemical Name | 2-N-(3H-benzimidazol-5-yl)-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine |
| Synonyms | APY 29; APY-29 |
| Molecular Formula | C17H16N8 |
| Molecular Weight | 332.363 |
| Smile | C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC5=C(C=C4)N=CN5 |
| InChiKey | WJNBSTLIALIIEW-UHFFFAOYSA-N |
| InChi | InChI=1S/C17H16N8/c1-2-10(1)13-8-16(25-24-13)22-15-5-6-18-17(23-15)21-11-3-4-12-14(7-11)20-9-19-12/h3-10H,1-2H2,(H,19,20)(H3,18,21,22,23,24,25) |
| CAS Number | 1216665-49-4 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
