Amuvatinib is a potent and multi-targeted inhibitor of c-Kit, PDGFR and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively.
For research use only. We do not sell to patients.
Chemical Information
| Name | Amuvatinib |
| Iupac Chemical Name | N-(1,3-benzodioxol-5-ylmethyl)-4-([1]benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide |
| Synonyms | MP-470; MP 470; MP470; HPK 56 |
| Molecular Formula | C23H21N5O3S |
| Molecular Weight | 447.510 |
| Smile | C1CN(CCN1C2=NC=NC3=C2OC4=CC=CC=C43)C(=S)NCC5=CC6=C(C=C5)OCO6 |
| InChiKey | FOFDIMHVKGYHRU-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H21N5O3S/c32-23(24-12-15-5-6-18-19(11-15)30-14-29-18)28-9-7-27(8-10-28)22-21-20(25-13-26-22)16-3-1-2-4-17(16)31-21/h1-6,11,13H,7-10,12,14H2,(H,24,32) |
| CAS Number | 850879-09-3 |
| Related CAS | |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
| Bulk | | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code | |
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| Mechanism | |
| Cell study | |
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