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Amuvatinib

Catalog No.: 123016
Cas No.: 850879-09-3
Purity : 98% 
123016 - Amuvatinib | CAS 850879-09-3

Catalog number : 123016

CAS number : 850879-09-3

Molecular Formula : C23H21N5O3S 

Molecular Weight : 447.510 

Iupac Chemical Name : N-(1,3-benzodioxol-5-ylmethyl)-4-([1]benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide 

Smile : C1CN(CCN1C2=NC=NC3=C2OC4=CC=CC=C43)C(=S)NCC5=CC6=C(C=C5)OCO6

InChiKey : FOFDIMHVKGYHRU-UHFFFAOYSA-N

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SynonymsMP-470; MP 470; MP470; HPK 56 
Molecular FormulaC23H21N5O3S 
Molecular Weight447.510 
AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileC1CN(CCN1C2=NC=NC3=C2OC4=CC=CC=C43)C(=S)NCC5=CC6=C(C=C5)OCO6
InChiKeyFOFDIMHVKGYHRU-UHFFFAOYSA-N
InChiInChI=1S/C23H21N5O3S/c32-23(24-12-15-5-6-18-19(11-15)30-14-29-18)28-9-7-27(8-10-28)22-21-20(25-13-26-22)16-3-1-2-4-17(16)31-21/h1-6,11,13H,7-10,12,14H2,(H,24,32)
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Amuvatinib is a potent and multi-targeted inhibitor of c-Kit, PDGFR and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively.
 

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