武汉永璨生物科技有限公司
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抑制剂/受体激动剂
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
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Pyrimidines
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产品名字索引 S
舒更葡糖钠
(Catalog# : 17011713, Cas# :
343306-79-6
)
舒更葡糖钠是治疗神经肌肉阻滞的药物。
链脲菌素
(Catalog# : 17011712, Cas# :
18883-66-4
)
链脲菌素是一种从链球菌中分离出来的甲基亚硝基脲类抗肿瘤抗生
Sotagliflozin
(Catalog# : 17011711, Cas# :
1018899-04-1
)
Sotagliflozin,也称为LX4211,是一种口服活性和双SGLT1 / SGLT2抑制剂,在
索利霉素
(Catalog# : 17011710, Cas# :
760981-83-7
)
索利霉素,也称为CEM-101和OP-1068, 是一种用于治疗社区获得性肺炎(C
SMER28
(Catalog# : 17011709, Cas# :
307538-42-7
)
SMER28是一种自噬的小分子调制器,在哺乳动物细胞中独立于雷帕霉
SKF-38393盐酸盐
(Catalog# : 17011707, Cas# :
62717-42-4
)
SKF-38393, 也称为(+/-)-SKF-38393, 是苯偶氮化学类的合成化合物,作为
西他沙星
(Catalog# : 17011706, Cas# :
127254-12-0
)
西他沙星是一种新型的广谱口服氟喹诺酮,它对许多革兰氏阳性、
SHP099盐酸盐
(Catalog# : 17011704, Cas# :
1801747-11-4
)
SHP099是一个强有力的、选择性、口服生物利用率和有效的IC50 = 0.0
6-姜烯酚
(Catalog# : 17011703, Cas# :
555-66-8
)
6-姜烯酚, 是姜的一种辛辣成分,类似于姜酚的化学结构。
SGC707
(Catalog# : 17011702, Cas# :
1687736-54-4
)
SGC707是一种强效、选择性和细胞活性的蛋白质精氨酸甲基转移酶3
SC66
(Catalog# : 17011701, Cas# :
871361-88-5
)
SC66是一种新型的有效的AKT抑制剂,在一定剂量和时间依赖性的方
SBI0206965
(Catalog# : 71161, Cas# :
1884220-36-3
)
SBI0206965是一种有效的选择性自噬激酶ULK1抑制剂。许多肿瘤变得沉
SB-743921盐酸盐
(Catalog# : 17011609, Cas# :
940929-33-9
)
SB-743921是一种具有潜在抗肿瘤性质的合成小分子。
Sardomozide
(Catalog# : 17011607, Cas# :
149400-88-4
)
Sardomozide,也叫SAM486A或CGP48664,是一种第二代聚胺合成抑制剂,抑制
SAR407899 HCl
(Catalog# : 17011606, Cas# :
923262-96-8
)
SAR407899是一种具有良好的抗高血压活性的强效和选择性的激酶抑制
SAR131675
(Catalog# : 17011605, Cas# :
1092539-44-0
)
SAR131675是一种有效的选择性vegfr - 3抑制剂。
4SC-202
(Catalog# : 161227110, Cas# :
910462-43-0
)
4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone de
SKL2001
(Catalog# : 16122784, Cas# :
909089-13-0
)
SKL2001 is a novel agonist of the Wnt/-catenin pathway that disrupts the Axin/-cateni
Salicylanilide
(Catalog# : 16122766, Cas# :
87-17-2
)
Salicylanilides are a group of compounds with a wide range of biological activities i
Sivelestat (ONO-5046)
(Catalog# : 16122760, Cas# :
127373-66-4
)
Sivelestat is a potent and selective inhibitor of neutrophil elastase with IC50 of 44
Sivelestat sodium
(Catalog# : 16122758, Cas# :
201677-61-4
)
Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, also inhib
SC75741
(Catalog# : 16122748, Cas# :
913822-46-5
)
SC75741 is a potent NF-B inhibitor with EC50 of 200 nM.SC75741 shows immunosuppressiv
SQ22536
(Catalog# : 16122726, Cas# :
17318-31-9
)
SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 M. It can inhibit PGE
SIS3
(Catalog# : 16122721, Cas# :
521984-48-5
)
SIS3, a novel specific inhibitor of Smad3, inhibits TGF- and activin signaling by sup
Saccharin 1-methylimidazole (SMI)
(Catalog# : 16122716, Cas# :
482333-74-4
)
SMI is considered a general-purpose activator for DNA and RNA synthesis.
STA-21
(Catalog# : 16122706, Cas# :
111540-00-2
)
STA-21 is a selective STAT3 inhibitor.In cells, STA-21 inhibits Stat3 DNA binding act
SKI II
(Catalog# : 6111526, Cas# :
312636-16-1
)
SKI-II is a synthetic inhibitor of sphingosine kinase (SK) activity with IC50 of 78 M
SR1001
(Catalog# : 6111522, Cas# :
1335106-03-0
)
SR1001 is a selective ROR and ROR inverse agonist; suppresses TH17 cell differentiati
S1P1 Agonist III
(Catalog# : 61119, Cas# :
1324003-64-6
)
S1P1 Agonist III is a potent and orally active S1P1 agonist with EC50 of 18 nM; no ac
SCH 546738
(Catalog# : 161113, Cas# :
906805-42-3
)
SCH 546738 is a novel, potent and non-competitive small molecule CXCR3 antagonist wit
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
----
SSTR
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
----
Hemoglobin
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
Osivelotor (别名: GBT-601; GBT-021601)
(Catalog# : 26A061, Cas# :
2417955-18-9
)
Osivelotor(同义词:GBT-601;GBT-021601)是下一代镰状血红蛋白(HbS)
Linvemastat (别名: FP-020)
(Catalog# : 26A060, Cas# :
2389060-50-6
)
Linvemastat(FP-020)是一种高效、选择性口服MMP-12抑制剂。
BLU-808
(Catalog# : 26A024, Cas# :
3041025-10-6
)
BLU-808是一种针对肥大细胞疾病的野生型c-KIT的强效且具有选择性的
SCO-240
(Catalog# : 26A059, Cas# :
1695564-98-7
)
SCO-240是一种研究性、口服活性和选择性生长抑素受体亚型5(SSTR5
N-Methylamisulpride ( 别名: LB-102 )
(Catalog# : 26A058, Cas# :
2227154-23-4
)
N-甲基咪唑胺(同义词:LB-102)是一种多巴胺D2和D3受体拮抗剂和血
Safusidenib Erbumine
(Catalog# : 25178, Cas# :
1898207-64-1
)
DS-1001 是一种口服的脑渗透性突变 IDH1 选择性抑制剂。
Repinatrabit ( 别称: JNT-517 )
(Catalog# : 26A056, Cas# :
2837993-05-0
)
Repinatrabit(JNT-517)是一种针对Phe转运蛋白SLC6A19的研究性、选择性
Privosegtor ( 别名: OCS-05, ACT-01 )
(Catalog# : 26A055, Cas# :
1361200-34-1
)
Privosegtor(OCS-05,ACT-01)是一种小分子拟肽、BDNF/NT-3生长因子受体
ART-6043
(Catalog# : 26A054, Cas# :
2923356-52-7
)
ART-6043是一种口服的DNA聚合酶θ(POLQ)小分子抑制剂。
Palacaparib ( Synonyms: AZD-9574 )
(Catalog# : 26A053, Cas# :
2756333-39-6
)
Palacioparib(AZD-9574)是一种口服的中枢神经系统渗透剂PARP-1抑制剂