武汉永璨生物科技有限公司
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抑制剂/受体激动剂
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
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定制合成
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订购信息
联系我们
公司简介
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产品名字索引 S
索利霉素
(Catalog# : 17011710, Cas# :
760981-83-7
)
索利霉素,也称为CEM-101和OP-1068, 是一种用于治疗社区获得性肺炎(C
SMER28
(Catalog# : 17011709, Cas# :
307538-42-7
)
SMER28是一种自噬的小分子调制器,在哺乳动物细胞中独立于雷帕霉
SKF-38393盐酸盐
(Catalog# : 17011707, Cas# :
62717-42-4
)
SKF-38393, 也称为(+/-)-SKF-38393, 是苯偶氮化学类的合成化合物,作为
西他沙星
(Catalog# : 17011706, Cas# :
127254-12-0
)
西他沙星是一种新型的广谱口服氟喹诺酮,它对许多革兰氏阳性、
SHP099盐酸盐
(Catalog# : 17011704, Cas# :
1801747-11-4
)
SHP099是一个强有力的、选择性、口服生物利用率和有效的IC50 = 0.0
6-姜烯酚
(Catalog# : 17011703, Cas# :
555-66-8
)
6-姜烯酚, 是姜的一种辛辣成分,类似于姜酚的化学结构。
SGC707
(Catalog# : 17011702, Cas# :
1687736-54-4
)
SGC707是一种强效、选择性和细胞活性的蛋白质精氨酸甲基转移酶3
SC66
(Catalog# : 17011701, Cas# :
871361-88-5
)
SC66是一种新型的有效的AKT抑制剂,在一定剂量和时间依赖性的方
SBI0206965
(Catalog# : 71161, Cas# :
1884220-36-3
)
SBI0206965是一种有效的选择性自噬激酶ULK1抑制剂。许多肿瘤变得沉
SB-743921盐酸盐
(Catalog# : 17011609, Cas# :
940929-33-9
)
SB-743921是一种具有潜在抗肿瘤性质的合成小分子。
Sardomozide
(Catalog# : 17011607, Cas# :
149400-88-4
)
Sardomozide,也叫SAM486A或CGP48664,是一种第二代聚胺合成抑制剂,抑制
SAR407899 HCl
(Catalog# : 17011606, Cas# :
923262-96-8
)
SAR407899是一种具有良好的抗高血压活性的强效和选择性的激酶抑制
SAR131675
(Catalog# : 17011605, Cas# :
1092539-44-0
)
SAR131675是一种有效的选择性vegfr - 3抑制剂。
4SC-202
(Catalog# : 161227110, Cas# :
910462-43-0
)
4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone de
SKL2001
(Catalog# : 16122784, Cas# :
909089-13-0
)
SKL2001 is a novel agonist of the Wnt/-catenin pathway that disrupts the Axin/-cateni
Salicylanilide
(Catalog# : 16122766, Cas# :
87-17-2
)
Salicylanilides are a group of compounds with a wide range of biological activities i
Sivelestat (ONO-5046)
(Catalog# : 16122760, Cas# :
127373-66-4
)
Sivelestat is a potent and selective inhibitor of neutrophil elastase with IC50 of 44
Sivelestat sodium
(Catalog# : 16122758, Cas# :
201677-61-4
)
Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, also inhib
SC75741
(Catalog# : 16122748, Cas# :
913822-46-5
)
SC75741 is a potent NF-B inhibitor with EC50 of 200 nM.SC75741 shows immunosuppressiv
SQ22536
(Catalog# : 16122726, Cas# :
17318-31-9
)
SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 M. It can inhibit PGE
SIS3
(Catalog# : 16122721, Cas# :
521984-48-5
)
SIS3, a novel specific inhibitor of Smad3, inhibits TGF- and activin signaling by sup
Saccharin 1-methylimidazole (SMI)
(Catalog# : 16122716, Cas# :
482333-74-4
)
SMI is considered a general-purpose activator for DNA and RNA synthesis.
STA-21
(Catalog# : 16122706, Cas# :
111540-00-2
)
STA-21 is a selective STAT3 inhibitor.In cells, STA-21 inhibits Stat3 DNA binding act
SKI II
(Catalog# : 6111526, Cas# :
312636-16-1
)
SKI-II is a synthetic inhibitor of sphingosine kinase (SK) activity with IC50 of 78 M
SR1001
(Catalog# : 6111522, Cas# :
1335106-03-0
)
SR1001 is a selective ROR and ROR inverse agonist; suppresses TH17 cell differentiati
S1P1 Agonist III
(Catalog# : 61119, Cas# :
1324003-64-6
)
S1P1 Agonist III is a potent and orally active S1P1 agonist with EC50 of 18 nM; no ac
SCH 546738
(Catalog# : 161113, Cas# :
906805-42-3
)
SCH 546738 is a novel, potent and non-competitive small molecule CXCR3 antagonist wit
4SC-202
(Catalog# : 611937, Cas# :
1186222-89-8
)
4SC-202 is an orally available potent HDACi specific for class I HDAC isoenzymes(NO H
SJB3-019A
(Catalog# : 611930, Cas# :
2070015-29-9
)
SJB3-019A is a potent and novel usp1 inhibitor. SJB3-019A (IC50 = 0.0781 uM) was 5 ti
SR-3029
(Catalog# : 611915, Cas# :
1454585-06-8
)
SR 3029 is a potent and highly specific CK1/CK1 inhibitor with the IC50 of 97 nM.SR-3
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive-Oxygen-Species-ROS
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
Mitoquinol mesylate (MitoQ)
(Catalog# : 26A042, Cas# :
845959-55-9
)
Mitoquinol mesylate (MitoQ) 是一种线粒体靶向抗氧化剂,具体而言,它
SPG-601 ( VSN-16R )
(Catalog# : 24042, Cas# :
1246960-09-7
)
SPG-601(原名VSN-16R)是一种口服给药、同类首创的小分子药物,是
LY3039478 ( Crenigacestat )
(Catalog# : 17021601, Cas# :
1421438-81-4
)
LY3039478 ( Crenigacestat ) 是一种选择性 NOTCH1 抑制剂,通过阻断 VEGFA/
PF-9366
(Catalog# : 184107, Cas# :
72882-78-1
)
PF-9366是一种新型的人蛋氨酸腺苷转移酶2A (Mat2A),肝外同种型。
MAT2A-IN-22
(Catalog# : 26A021, Cas# :
2925330-18-1
)
MAT2A-IN-22 (Compound 29-1) 是一种可透过血脑屏障的和口服有效的 MAT2A
Pantothenate kinase-IN-3
(Catalog# : 26A041)
泛酸激酶-IN-3(亦称化合物21,https://doi.org/10.1021/acs.jmedchem.5c03452)
Claziprotamidum ( Claziprotamide ; BBP-671 )
(Catalog# : 26A040, Cas# :
2361124-03-8
)
Claziprotamidum(Claziprotamide;BBP-671)是一种强效、口服有效且能透过
PZ-3022
(Catalog# : 26A039, Cas# :
2170608-85-0
)
PZ-3022是一种别构型的PanK激活剂,能够抵消C3-CoA的抑制作用。
PZ-2891
(Catalog# : 193282, Cas# :
2170608-82-7
)
PZ-2891是一种强效的、选择性的、口服活性泛酸激酶(PANK)调制剂,
Pantothenate kinase-IN-2
(Catalog# : 26A038, Cas# :
902614-04-4
)
Pantothenate kinase-IN-2是一种泛酸激酶抑制剂,对PanK2的IC50值为92 nM,