SQ22536
编号: 16122726
Cas号: 17318-31-9
纯度: 98%
SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 M. It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets.SQ22536(250 mol/L) attenuates the inhibitory effect of adenosine against ADP-induced platelet aggregation from 85 to 575%, respectively (p<0.001). SQ22536 also attenuates an increase of intraplatelet levels of cAMP by adenosine from 292 to 91 pmol/108 platelets (p<0.05). It has no effect on the platelet antiaggregant activity of inosine (1 to 4 mmol/L) and ADP-induced platelet aggregation
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | SQ22536 |
|---|---|
| Iupac 化学名称 | SQ22536 |
| 同义词 | 9-(tetrahydrofuran-2-yl)-9h-purin-6-amine |
| 英文同义词 | 9-(tetrahydrofuran-2-yl)-9h-purin-6-amine |
| 分子式 | C9H11N5O |
| 分子量 | 205.22 |
| Smile | c1nc(c2c(n1)n(cn2)C3CCCO3)N |
| InChiKey | UKHMZCMKHPHFOT-UHFFFAOYSA-N |
| InChi | InChI=1S/C9H11N5O/c10-8-7-9(12-4-11-8)14(5-13-7)6-2-1-3-15-6/h4-6H,1-3H2,(H2,10,11,12) |
| Cas号 | 17318-31-9 |
| MDL | MFCD00210216 |
| 相关CAS号 |
订购信息
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