Sotagliflozin
编号: 17011711
Cas号: 1018899-04-1
纯度: 98%
Sotagliflozin, also known as LX4211, is an orally active and a dual SGLT1/SGLT2 inhibitor, which improves glycemic control in patients with type 2 diabetes in a randomized, placebo-controlled trial. LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1 (SGLT1)-mediated absorption of intestinal glucose. Sotagliflozin is currently being developed by Lexicon for the treatment of type 1 and type 2 diabetes mellitus. Sotagliflozin may be an effective and promising medication for treating not only Type 2 diabetes (the common target for non-insulin medications for diabetes), but also Type 1 as well.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Sotagliflozin |
|---|---|
| Iupac 化学名称 | (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol |
| 同义词 | LX4211; LX 4211; LX 4211 |
| 英文同义词 | LX4211; LX 4211; LX 4211 |
| 分子式 | C21H25ClO5S |
| 分子量 | 424.94 |
| Smile | ClC1=C(C=C(C=C1)[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)SC)CC1=CC=C(C=C1)OCC |
| InChiKey | QKDRXGFQVGOQKS-CRSSMBPESA-N |
| InChi | InChI=1S/C21H25ClO5S/c1-3-26-15-7-4-12(5-8-15)10-14-11-13(6-9-16(14)22)20-18(24)17(23)19(25)21(27-20)28-2/h4-9,11,17-21,23-25H,3,10H2,1-2H3/t17-,18-,19+,20+,21-/m1/s1 |
| Cas号 | 1018899-04-1 |
| 相关CAS号 |
订购信息
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