武汉永璨生物科技有限公司
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抑制剂/受体激动剂
Angiogenesis
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Apoptosis
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MAPK
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Metabolism
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NF-κB
Protein Tyrosine Kinase
Proteases
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TGF-beta/Smad
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Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
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分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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订购信息
联系我们
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 S
Senaparib
(Catalog# : 20103002, Cas# :
1401682-78-7
)
Senaparib (IMP4297) is a novel agent targeting PARP (poly-ADP ribose polymerase) with
SAR131675
(Catalog# : 2091901, Cas# :
1433953-83-3
)
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine
(1S,5R)-1-(3-fluorophenyl)-3-oxabicyclo[3.1.0]hexan-2-one
(Catalog# : 2091205, Cas# :
528587-70-4
)
SJB2-043
(Catalog# : 2071609, Cas# :
63388-44-3
)
SJB2-043 is an inhibitor of USP1 target ID1 degradation in leukemic cells.
Spastazoline
(Catalog# : 2071521, Cas# :
2351882-11-4
)
Spastazoline is a novel inhibitor for aaa+ (atpases associated with diverse cellular
SB 225002
(Catalog# : 2071510, Cas# :
18298-32-4
)
SCH-23390 maleate
(Catalog# : 2071501, Cas# :
87134-87-0
)
SCH-23390 hydrochloride is a potent dopamine receptor antagonist (Ki values are 0.2 n
((1S,2R)-1-(3-fluorophenyl)cyclopropane-1,2-diyl)dimethanol
(Catalog# : 202331, Cas# :
1369767-20-3
)
我们可以提供公斤级定制合成。((1S,2R)-1-(3-fluorophenyl)cyclopropane-1,2
(S)-4-(((1-Propyl-1H-imidazol-5-yl)methyl)sulfinyl)aniline
(Catalog# : 2062002, Cas# :
497223-38-8
)
SJ000291942
(Catalog# : 2051514, Cas# :
425613-09-8
)
SJ000291942 is a bone morphogenic protein (BMP) signaling activator.
Selinexor HCl
(Catalog# : 2051502, Cas# :
Unknown (HCl)
)
Selinexor, also known as KPT-330, is an orally bioavailable, potent and selective XPO
Selinexor free base
(Catalog# : 2051501, Cas# :
1393477-72-9 (free base)
)
Selinexor, also known as KPT-330, is an orally bioavailable, potent and selective XPO
Simurosertib
(Catalog# : 2041504, Cas# :
1330782-76-7
)
Simurosertib, also known as TAK-931, is an orally bioavailable inhibitor of cell divi
SGC2085 free base
(Catalog# : 204609, Cas# :
1821908-48-8 (free base)
)
SGC2085 is a Potent and Selective Coactivator Associated Arginine Methyltransferase 1
Segetalin B
(Catalog# : 204501, Cas# :
164991-89-3
)
Segetalin B is natural product isolated from Seeds of Vaccaria Segetalis. Segetalin B
S26131
(Catalog# : 112592, Cas# :
296280-56-3
)
S26131 is a bioactive chemical.
SI-113
(Catalog# : 111896, Cas# :
1392816-46-4
)
SI113 is a specific inhibitor of the Sgk1 kinase activity, counteracting cancer cell
IPI145中间体
(Catalog# : 196301, Cas# :
1350643-72-9
)
Selisistat ( EX-527 )
(Catalog# : 52001, Cas# :
49843-98-3
)
Selisistat 是第一个确定的有效且可渗透细胞的 SIRT1 特异性抑制剂,
ST-193
(Catalog# : 193261, Cas# :
489416-12-8
)
ST-193是一种有效的广谱沙粒病毒抑制剂。抑制Guanarito、Junin、Lassa
SPL-707
(Catalog# : 193209, Cas# :
2195361-33-0
)
SPL-707是第一种选择性口服活性SPPL2a抑制剂。密切相关的酶γ-secret
SHP394
(Catalog# : 193122, Cas# :
2055757-40-7
)
SHP394是一种有效的口服SHP2抑制剂(IC50 = 23nm),具有高亲脂性、增强
SGC-GAK-1
(Catalog# : 193113, Cas# :
2226517-76-4
)
SGC-GAK-1是一种针对atp结合位点的高效选择性GAK激酶探查。
SU 5214
(Catalog# : 19314, Cas# :
186611-04-1
)
SU 5214是酪氨酸激酶信号转导的调制器。
Silvestrol
(Catalog# : 192278, Cas# :
697235-38-4
)
Silvestrol,一种黄酮类化合物家族的成员,在体外和体内,从属的
Selpercatinib
(Catalog# : 192276, Cas# :
2152628-33-4
)
Selpercatinib是一种具有抗肿瘤作用的酪氨酸激酶抑制剂。
SM16
(Catalog# : 192215, Cas# :
614749-78-9
)
SM16是一种新型类型I的TGF-β信号传导抑制剂。
SB-674042
(Catalog# : 192151, Cas# :
483313-22-0
)
SB-674042是一种有效的选择性OX1R拮抗剂。SB-674042与OX1R高亲和力结合
Seclidemstat
(Catalog# : 192147, Cas# :
1423715-37-0
)
Seclidemstat是一种抗肿瘤药物候选药物。
Setafrastat
(Catalog# : 192146, Cas# :
1399715-48-0
)
Setafrastat是一种转胺酶抑制剂和血管内皮生长因子(VEGF)促进剂。
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
Temozolomide
(Catalog# : 25209, Cas# :
85622-93-1
)
替莫唑胺是一种烷化剂。
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 是一种口服生物可利用的 SPT 抑制剂,比多球菌素更有效,
Opakalim
(Catalog# : 25193, Cas# :
2376397-93-0
)
Opakalim(BHV-7000)是Kv7.2/7.3钾通道(KCNQ2/3)的口服小分子激活剂,
PF-06835919 ( MDK-1846 )
(Catalog# : 193264, Cas# :
2102501-84-6
)
MDK1846是一种强效的酮己糖激酶(KHK)抑制剂。
MK256
(Catalog# : 25208, Cas# :
2271348-04-8
)
MK256是一种新型CDK8抑制剂,通过下调STAT通路在急性髓系白血病(
NSD1 抑制剂 BT5
(Catalog# : 25207, Cas# :
2351225-46-0
)
BT5可有效抑制NSD1,与细胞中的SET结构域结合,并降低H3K36me2水平。
MA242 TFA
(Catalog# : 25206, Cas# :
1049704-18-8
)
MA242是一种MDM2和NFAT1双重抑制剂,可诱导MDM2自泛素化及降解,并抑
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 )是一种口服选择性成纤维细胞生长因子受体3(
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B 是一种高效、选择性变构 M1 毒蕈碱和 σ1 受体激动剂。 AF710
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A抑制剂5具有抑制MAT2A的高效力和对MTAP缺失的癌症细胞系的显著