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LY2228820

Catalog No.: 122509
Cas No.: 862507-23-1
Purity : 98% 
122509 - LY2228820 | CAS 862507-23-1

Catalog number : 122509

CAS number : 862507-23-1

分子式 : C26H37FN6O6S2 

分子量 : 612.737 

Iupac 化学名称 : 5-[2-tert-butyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)imidazo[4,5-b]pyridin-2-amine;methanesulfonic acid 

Smile : CC(C)(C)CN1C2=C(C=CC(=N2)C3=C(N=C(N3)C(C)(C)C)C4=CC=C(C=C4)F)N=C1N.CS(=O)(=O)O.CS(=O)(=O)O

InChiKey : NARMJPIBAXVUIE-UHFFFAOYSA-N

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同义词Ralimetinib dimesylate; LY2228820 dimesylate; LY2228820 2MsOH; LY 2228820; LY-2228820 
英文同义词Ralimetinib dimesylate; LY2228820 dimesylate; LY2228820 2MsOH; LY 2228820; LY-2228820 
分子式C26H37FN6O6S2 
分子量612.737 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC(C)(C)CN1C2=C(C=CC(=N2)C3=C(N=C(N3)C(C)(C)C)C4=CC=C(C=C4)F)N=C1N.CS(=O)(=O)O.CS(=O)(=O)O
InChiKeyNARMJPIBAXVUIE-UHFFFAOYSA-N
InChiInChI=1S/C24H29FN6.2CH4O3S/c1-23(2,3)13-31-20-17(28-22(31)26)12-11-16(27-20)19-18(14-7-9-15(25)10-8-14)29-21(30-19)24(4,5)6;2*1-5(2,3)4/h7-12H,13H2,1-6H3,(H2,26,28)(H,29,30);2*1H3,(H,2,3,4)
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LY2228820 is a novel and potent p38MAPK inhibitor (the IC50 for p38MAPK and p38MAPK were 7 nM and 3 nM, respectively). 

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