Lifitegrast
Catalog No: 16071412
CAS Number: 1025967-78-5
Purity: 98% by HPLC
Lifitegrast, also known as SAR-1118, is an LFA-1 antagonist intended for the treatment of vascular complications of the eye. Lifitegrast inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1), thus lessening overall inflammatory responses.
仅供研究使用。 我们不向患者出售。
Chemical Information
| Name | Lifitegrast |
|---|---|
| Iupac Chemical Name | (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid |
| Synonyms | SAR-1118; SAR 1118 |
| 英文同义词 | SAR-1118; SAR 1118 |
| Molecular Formula | C29H24Cl2N2O7S |
| Molecular Weight | 615.478 |
| Smile | O1C=CC2=C1C=C(C=C2)C(=O)N2CC1=CC(=C(C(=C1CC2)Cl)C(=O)N[C@H](C(=O)O)CC2=CC(=CC=C2)S(=O)(=O)C)Cl |
| InChiKey | JFOZKMSJYSPYLN-QHCPKHFHSA-N |
| InChi | InChI=1S/C29H24Cl2N2O7S/c1-41(38,39)20-4-2-3-16(11-20)12-23(29(36)37)32-27(34)25-22(30)13-19-15-33(9-7-21(19)26(25)31)28(35)18-6-5-17-8-10-40-24(17)14-18/h2-6,8,10-11,13-14,23H,7,9,12,15H2,1H3,(H,32,34)(H,36,37)/t23-/m0/s1 |
| CAS Number | 1025967-78-5 |
| 相关CAS号 |
Ordering Information
| 包装 | Price | 库存 | Purity | 备货期 |
|---|---|---|---|---|
| 大货 | Enquiry | Enquiry | Enquiry |
| 外观性状 | Solid powder |
|---|---|
| Purity | 98% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| 处理方式 | |
| Shipping Condition | Shipped under ambient temperature |
| 海关编码 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
