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Linifanib

Catalog No.: 121416
Cas No.: 796967-16-3
Purity : 98% 
121416 - Linifanib | CAS 796967-16-3

Catalog number : 121416

CAS number : 796967-16-3

分子式 : C21H18FN5O 

分子量 : 375.399 

Iupac 化学名称 : 1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea 

Smile : CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N

InChiKey : MPVGZUGXCQEXTM-UHFFFAOYSA-N

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同义词ABT-869; AL-39324; ABT 869; ABT869; AL 39324; AL39324 
英文同义词ABT-869; AL-39324; ABT 869; ABT869; AL 39324; AL39324 
分子式C21H18FN5O 
分子量375.399 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N
InChiKeyMPVGZUGXCQEXTM-UHFFFAOYSA-N
InChiInChI=1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)
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Linifanib is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR, CSF-1R, Flt-1/3 and PDGFR with IC50 of 4 nM, 3 nM, 3 nM/4 nM and 66 nM respectively. 

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