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Linsitinib

Catalog No.: 010819
Cas No.: 867160-71-2
Purity : 98% 
010819 - Linsitinib | CAS 867160-71-2

Catalog number : 010819

CAS number : 867160-71-2

分子式 : C26H23N5O 

分子量 : 421.494 

Iupac 化学名称 : 3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol 

Smile : CC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O

InChiKey : PKCDDUHJAFVJJB-UHFFFAOYSA-N

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同义词OSI 906; OSI-906; OSI906 
英文同义词OSI 906; OSI-906; OSI906 
分子式C26H23N5O 
分子量421.494 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O
InChiKeyPKCDDUHJAFVJJB-UHFFFAOYSA-N
InChiInChI=1S/C26H23N5O/c1-26(32)14-19(15-26)25-30-22(23-24(27)28-11-12-31(23)25)18-8-7-17-9-10-20(29-21(17)13-18)16-5-3-2-4-6-16/h2-13,19,32H,14-15H2,1H3,(H2,27,28)
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Linsitinib is highly potent, orally efficacious and highly selective, dual ATP-competitive inhibitor of IGF-1R (IC50= 35 nM) and insulin receptor (IC50=75 nM).
 

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