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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
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定制合成
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订购信息
联系我们
公司简介
联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
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定制合成
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订购信息
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公司简介
联系我们
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产品名字索引 I
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产品名字索引 I
Itacitinib
(Catalog# : 6111505, Cas# :
1334298-90-6
)
Itacitinib (INCB039110) is an oral selective JAK1 inhibitor. Itacitinib is an inh
IC261
(Catalog# : 611914, Cas# :
186611-52-9
)
IC261 is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50
Imeglimin
(Catalog# : 611811, Cas# :
775351-65-0
)
Imeglimin(EMD-387008) is the first in a new tetrahydrotriazine-containing class of or
IC-87114
(Catalog# : 160926004, Cas# :
371242-69-2
)
It Inhibits p110, p110 and p110 only at much higher concentrations. It does not inhib
Iniparib
(Catalog# : 16071103, Cas# :
160003-66-7
)
Iniparib, also known as BSI-201, is a small-molecule prodrug inhibitor of the nuclear
Idasanutlin (RG7388)
(Catalog# : 16070812, Cas# :
1229705-06-9
)
Idasanutlin; also known as RG7388 and RO5503781, is a highly potent and selective MDM
Istradefylline
(Catalog# : 16070809, Cas# :
155270-99-8
)
Istradefylline (KW-6002) is a selective antagonist at the A2A receptor. It has been f
Ilomastat
(Catalog# : 16070104, Cas# :
142880-36-2
)
Ilomastat (GM6001) 是一种有效、广谱的基质金属蛋白酶 (MMP) 抑制剂,
IRAK-1-4 Inhibitor I
(Catalog# : 16062116, Cas# :
448906-42-1
)
IRAK-1-4 Inhibitor I
Ivosidenib
(Catalog# : 16053001, Cas# :
1448347-49-6
)
Ivosidenib is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1)
INCB 024360
(Catalog# : 032405, Cas# :
1204669-58-8
)
INCB 024360 is a potent and novel indoleamine-2,3 dioxygenase (IDO)inhibitor with an
5-Iodo-2-isopropyl-1-methyl-1H-imidazole
(Catalog# : 021701, Cas# :
851870-28-5
)
Coming soon!
Irbinitinib
(Catalog# : 011310, Cas# :
937263-43-9
)
Irbinitinib is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent ag
INK-128
(Catalog# : 011121, Cas# :
1224844-38-5
)
INK 128 is a potent and selective mTOR inhibitor with IC50 of 1 nM; >200-fold less
IWP L6
(Catalog# : 011109, Cas# :
1427782-89-5
)
IWP L6 is a Porcn inhibitor with EC50 of 0.5 nM.
Icotinib
(Catalog# : 011101, Cas# :
610798-31-7
)
Icotinib is an orally available quinazoline-based inhibitor of epidermal growth facto
IWP-3
(Catalog# : 010801, Cas# :
687561-60-0
)
IWP-3 is an inhibitor of Wnt production.
Isoquinolin-7-ylboronic acid
(Catalog# : 010612, Cas# :
1092790-21-0
)
This product is for custom synthesis.
IKK 16
(Catalog# : 010419, Cas# :
1186195-62-9
)
Coming soon!
IDO-IN-2
(Catalog# : 123002, Cas# :
914471-09-3
)
IDO-IN-2 is a potent IDO1 inhibitor(IC50=10 nM) with desirable pharmaceutical propert
INT-747
(Catalog# : 122905, Cas# :
459789-99-2
)
INT-747 is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestati
ICG-001
(Catalog# : 122801, Cas# :
780757-88-2
)
ICG-001 is a potent, specific inhibitor of the canonical Wnt signaling pathway in can
Ixabepilone
(Catalog# : 122307, Cas# :
219989-84-1
)
Ixabepilone is an epothilone B analog and nontaxane microtubule-stabilizing compound
Isavuconazole
(Catalog# : 120801, Cas# :
241479-67-4
)
Coming soon!
IRAK-1-4 Inhibitor I
(Catalog# : 110907, Cas# :
509093-47-4
)
IRAK-1-4 Inhibitor I is a IRAK-4 Inhibitor with IC50 of 200 nM, and is an anti-inflam
IWP-2
(Catalog# : 110602, Cas# :
686770-61-6
)
IWP-2 is an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signal
Indiplon
(Catalog# : 102701, Cas# :
325715-02-4
)
Indiplon is a pyrazolopyrimidine that acts as a high-affinity positive allosteric mod
INH6
(Catalog# : 102620, Cas# :
1001753-24-7
)
INH6 is a potent Hec1 inhibitor, which specifically disrupts the Hec1/Nek2 interactio
INH1
(Catalog# : 102606, Cas# :
313553-47-8
)
INH1 is a small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cel
ITD-1
(Catalog# : 101902, Cas# :
1099644-42-4
)
ITD-1 is a selective inhibitor of TGF- signaling, displays little or no inhibition of
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
PLX8394
(Catalog# : 20613, Cas# :
1393466-87-9
)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil 是一种有效的、高选择性的口服活性抑制剂,针对 Rho 相关
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib 是一种口服、有效、选择性的小分子抑制剂,针对 menin 和
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib是一种在研口服丝裂原活化蛋白激酶活化蛋白激酶2(MK2
Zongertinib ( BI 1810631 )
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] 是一种人表皮生长因子受体 2 (HER2) 抑制剂。
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib是一种作用于非受体酪氨酸蛋白激酶 (TYK2)靶点的抑制
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 为BRD4降解剂,其在小鼠荷瘤异种移植模型中展现出显著抑
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) 是一种抗纤维化剂,降低胶原蛋白 I 和 III 的 mRNA
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) 是一种有效的 EGFR 抑制剂。
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).