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ISX-9

Catalog No.: 17022713
Cas No.: 832115-62-5
Purity : 98% 
17022713 - ISX-9 | CAS 832115-62-5

Catalog number : 17022713

CAS number : 832115-62-5

分子式 : C11H10N2O2S 

分子量 : 234.27 

Iupac 化学名称 : ISX-9 

Smile : c1cc(sc1)c2cc(no2)C(=O)NC3CC3

InChiKey : SYENTKHGMVKGAQ-UHFFFAOYSA-N

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同义词Isoxazole 9 
英文同义词Isoxazole 9 
分子式C11H10N2O2S 
分子量234.27 
外观类白色至白色固体
纯度98% 
可溶性可溶于DMSO
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
运输条件可在常温下运输
Smilec1cc(sc1)c2cc(no2)C(=O)NC3CC3
InChiKeySYENTKHGMVKGAQ-UHFFFAOYSA-N
InChiInChI=1S/C11H10N2O2S/c14-11(12-7-3-4-7)8-6-9(15-13-8)10-2-1-5-16-10/h1-2,5-7H,3-4H2,(H,12,14)
MDLMFCD04133937
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ISX-9 is a neurogenic agent. Isx-9 promotes neurogenesis in vivo, enhancing the proliferation and differentiation of hippocampal subgranular zone (SGZ) neuroblasts, and the dendritic arborization of adult-generated dentate gyrus neurons. Isx-9 also improves hippocampal function, enhancing memory in the Morris water maze. Notably, Isx-9 enhances neurogenesis and memory without detectable increases in cellular or animal activity or vascularization. Isx-9 enhances hippocampal neurogenesis and memory in vivo, and its effects are reliant on Mef2, revealing a novel cell-intrinsic molecular pathway regulating adult neurogenesis. 

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