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IC87201

Catalog No.: 16122820
Cas No.: 866927-10-8
Purity : 98% 
16122820 - IC87201 | CAS 866927-10-8

Catalog number : 16122820

CAS number : 866927-10-8

分子式 : C13H10Cl2N4O 

分子量 : 309.15 

Iupac 化学名称 : IC87201 

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同义词IC-87201; IC 87201 
英文同义词IC-87201; IC 87201 
分子式C13H10Cl2N4O 
分子量309.15 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
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IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular experiments and animal models of ischemic stroke and pain. IC87201 inhibited the in vitro binding of nNOS with PSD95, without inhibiting nNOS catalytic activity. nNOS-PSD95 interaction is important in maintaining hypersensitivity in acute and chronic pain. Disruption of the nNOS-PSD95 interaction provides a novel approach to obtain selective anti-hyperalgesic compounds. 

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