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IC261

编号: 611914
Cas号: 186611-52-9
纯度: 98% 

IC261 is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 M and for Cdk5 is 4.5 mM. 

IC261 is a specific inhibitor of the protein kinases casein kinase 1-delta and -epsilon, triggers the mitotic checkpoint and induces p53-dependent postmitotic effects. At low micromolar concentrations IC261 inhibits cytokinesis causing a transient mitotic arrest. IC261 selectively inhibits CK1 compared to other protein kinases by an ATP-competitive mechanism. 

 

仅供研究使用。 我们不向患者出售。

化学信息

名称IC261
Iupac 化学名称IC261 
同义词IC-261; SU-5607 
英文同义词IC-261; SU-5607 
分子式C18H17NO4 
分子量311.33 
SmileCOc1cc(c(c(c1)OC)/C=C/2\c3ccccc3NC2=O)OC
InChiKeyJBJYTZXCZDNOJW-JLHYYAGUSA-N
InChiInChI=1S/C18H17NO4/c1-21-11-8-16(22-2)14(17(9-11)23-3)10-13-12-6-4-5-7-15(12)19-18(13)20/h4-10H,1-3H3,(H,19,20)/b13-10+
Cas号186611-52-9
MDLMFCD00118156
相关CAS号

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包装价格库存纯度备货期
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外观性状crystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

611914 - IC261 | CAS 186611-52-9

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