SGI-110
Catalog No: 011806
CAS Number: 929901-49-5
Purity: 98%
SGI-110 is a small molecule, DNMT inhibitor with demonstrated activity in restoring silenced tumor suppressor gene expression in cancer cells by reversal of DNA methylation.
For research use only. We do not sell to patients.
Chemical Information
| Name | SGI-110 |
|---|---|
| Iupac Chemical Name | [(2S,3R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl [5-(4-amino-2-oxo-1,3,5-triazin-1-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate |
| Synonyms | Guadecitabine |
| Molecular Formula | C18H24N9O10P |
| Molecular Weight | 557.138 |
| Smile | C1C(C(OC1N2C=NC3=C2NC(=NC3=O)N)COP(=O)(O)OC4CC(OC4CO)N5C=NC(=NC5=O)N)O |
| InChiKey | GUWXKKAWLCENJA-UHFFFAOYSA-N |
| InChi | InChI=1S/C18H24N9O10P/c19-16-22-6-27(18(31)25-16)12-2-8(9(3-28)35-12)37-38(32,33)34-4-10-7(29)1-11(36-10)26-5-21-13-14(26)23-17(20)24-15(13)30/h5-12,28-29H,1-4H2,(H,32,33)(H2,19,25,31)(H3,20,23,24,30) |
| CAS Number | 929901-49-5 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
