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SGI-110

Catalog No.: 011806
Cas No.: 929901-49-5
Purity : 98% 
011806 - SGI-110 | CAS 929901-49-5

Catalog number : 011806

CAS number : 929901-49-5

Molecular Formula : C18H24N9O10P 

Molecular Weight : 557.138 

Iupac Chemical Name : [(2S,3R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl [5-(4-amino-2-oxo-1,3,5-triazin-1-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate 

Smile : C1C(C(OC1N2C=NC3=C2NC(=NC3=O)N)COP(=O)(O)OC4CC(OC4CO)N5C=NC(=NC5=O)N)O

InChiKey : GUWXKKAWLCENJA-UHFFFAOYSA-N

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SynonymsGuadecitabine 
Molecular FormulaC18H24N9O10P 
Molecular Weight557.138 
AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileC1C(C(OC1N2C=NC3=C2NC(=NC3=O)N)COP(=O)(O)OC4CC(OC4CO)N5C=NC(=NC5=O)N)O
InChiKeyGUWXKKAWLCENJA-UHFFFAOYSA-N
InChiInChI=1S/C18H24N9O10P/c19-16-22-6-27(18(31)25-16)12-2-8(9(3-28)35-12)37-38(32,33)34-4-10-7(29)1-11(36-10)26-5-21-13-14(26)23-17(20)24-15(13)30/h5-12,28-29H,1-4H2,(H,32,33)(H2,19,25,31)(H3,20,23,24,30)
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SGI-110 is a small molecule, DNMT inhibitor with demonstrated activity in restoring silenced tumor suppressor gene expression in cancer cells by reversal of DNA methylation. 

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