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Membrane Transporter/Ion Channel
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
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Name Index R
RU-SKI 43
(Catalog# : 6111503, Cas# :
1043797-53-0
)
RU-SKI 43 is a small molecule inhibitor of Hhat(Hedgehog acyltransferase), the enzyme
Roquinimex
(Catalog# : 6111413, Cas# :
84088-42-6
)
Roquinimex (Linomide; PNU212616; ABR212616) is a quinoline derivative immunostimulant
RHPS4
(Catalog# : 6111024, Cas# :
390362-78-4
)
RHPS4 is a potent inhibitor of Telomerase at submicromolar.
RGB-286638
(Catalog# : 611924, Cas# :
784210-87-3
)
RGB-286638 is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin
RK-33
(Catalog# : 611909, Cas# :
1070773-09-9
)
RK-33 is an RNA helicase inhibitor against DDX3, and inhibit its helicase activity.RK
RO8994
(Catalog# : 1673101, Cas# :
1309684-94-3
)
RO8994 is a potent and selective spiroindolinone MDM2 inhibitor for cancer therapy.
RO5045337
(Catalog# : 16071112, Cas# :
939981-39-2
)
RO5045337, also known as R7112, RG7112, is a MDM2 antagonist with potential antineopl
RSL 3
(Catalog# : 16070103, Cas# :
1219810-16-8
)
RSL 3
(R) QuinoxP(R)
(Catalog# : 16062107, Cas# :
866081-62-1
)
(R) QuinoxP(R)
Ro41-1049(HCl)
(Catalog# : 166154, Cas# :
127500-84-9
)
Ro 41-1049 is an inhibitor of the enzyme monoamine oxidase type A(MAO-A).
RS-1
(Catalog# : 16061501, Cas# :
312756-74-4
)
4-BroMo-N-(4-broMophenyl)-3-[[(phenylMethyl)aMino]sulfonyl]benzaMide;RAD51-stimulator
Relugolix
(Catalog# : 16060701, Cas# :
737789-87-6
)
Relugolix, also known as TAK-385, is a luteinizing hormone-releasing hormone (LH-RH)
RO31-8220 mesylate
(Catalog# : 16060303, Cas# :
138489-18-6
)
Ro 31-8220 is a PKC-inhibitor, which inhibits stimulated fluid pinocytosis of human P
R112
(Catalog# : 031003, Cas# :
575474-82-7
)
R112 is an ATP-competitive inhibitor of Syk kinase with a Ki of 96 nM. R112 inhibits
Ro 46-2005
(Catalog# : 031001, Cas# :
150725-87-4
)
Ro 46-2005 is a novel synthetic non-peptide endothelin receptor antagonist, inhibits
RAD140
(Catalog# : 030909, Cas# :
1182367-47-0
)
Coming soon!
Robalzotan tartrate hydrate
(Catalog# : 011907, Cas# :
169758-66-1
)
Coming soon!
Radotinib
(Catalog# : 011307, Cas# :
926037-48-1
)
Radotinib is an orally available, a second-generation tyrosine kinase inhibitor of Bc
Ruxolitinib
(Catalog# : 01118, Cas# :
941678-49-5
)
Ruxolitinib is the first potent, selective, JAK1/2 inhibitor to enter the clinic with
Ro 5126766
(Catalog# : 010812, Cas# :
946128-88-7
)
Ro 5126766 is a potent and selective dual RAF/MEK inhibitor. For SK-MEL-28, SK-MEL-2,
Refametinib
(Catalog# : 010810, Cas# :
923032-37-5
)
Refametinib is an orally bioavailable selective MEK inhibitor with potential antineop
Raltegravir
(Catalog# : 010412, Cas# :
518048-05-0
)
Raltegravir is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in
Ridaforolimus
(Catalog# : 123018, Cas# :
572924-54-0
)
Ridaforolimus is a selective mTOR inhibitor with IC50 of 0.2 nM; while not classified
R428
(Catalog# : 123010, Cas# :
1037624-75-1
)
R428 is a potent and selective small-molecule inhibitor(IC50=14 nM), blocks the activ
Rucaparib
(Catalog# : 123005, Cas# :
283173-50-2
)
Rucaparib is an inhibitor of PARP with Ki of 1.4 nM for PARP1, also showing binding a
RO4929097
(Catalog# : 123001, Cas# :
847925-91-1
)
RO4929097 is a secretase inhibitor with IC50 of 4 nM, inhibiting cellular processing
R788
(Catalog# : 122928, Cas# :
901119-35-5
)
Fostamatinib is a small molecule Syk kinase inhibitor with potential anti-inflammator
R406 free base
(Catalog# : 122927, Cas# :
841290-80-0
)
R406 is a potent inhibitor of immunoglobulin E (IgE)- and IgG-mediated activation of
RGB-286638 free base
(Catalog# : 122917, Cas# :
784210-88-4
)
RGB-286638 is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin
Ravidasvir hydrochloride
(Catalog# : 122904, Cas# :
1303533-81-4
)
Ravidasvir is a second-generation, orally active, potent and selective HCV NS5A prote
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1
Acoramidis hydrochloride
(Catalog# : 24068, Cas# :
2242751-53-5
)
Acoramidis is an oral, potent, and highly selective small molecule transthyretin (TTR
Crelosidenib
(Catalog# : 24101, Cas# :
2230263-60-0
)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor.
LOXO-435
(Catalog# : 25080, Cas# :
2833703-74-3
)
LOXO-435 is a selective small molecule inhibitor of FGFR3. It is active against both
MAT2A-IN-9
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 (compound 167), a 2-oxoquinazoline derivative, is a potent MAT2A (methioni
Gridegalutamide
(Catalog# : 25138, Cas# :
2446928-30-7
)
Gridegalutamide, also known as BMS-986365 and CC-94676, is a heterobifunctional, firs
Chiauranib
(Catalog# : 25146, Cas# :
1256349-48-0
)
Chiauranib also known as orally available, small molecule inhibitor of select serine-
Atuzabrutinib
(Catalog# : 25145, Cas# :
1581714-49-9
)
Atuzabrutinib, also known as PRN 473, is a Bruton's tyrosine kinase inhibitor.
Andamertinib
(Catalog# : 25144, Cas# :
2254145-43-0
)
Andamertinib is an epidermal growth factor receptor tyrosine kinase inhibitor. It is
MEN-1703
(Catalog# : 25143, Cas# :
2769008-22-0
)