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Inhibitors & Agonists
Angiogenesis
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MAPK
Membrane Transporter/Ion Channel
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Neuronal Signaling
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Protein Tyrosine Kinase
Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
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Name Index R
Regadenoson
(Catalog# : 1810224, Cas# :
313348-27-5
)
Regadenoson is an A2A adenosine receptor agonist that is a coronary vasodilator that
RMC-4550
(Catalog# : 186251, Cas# :
2172651-73-7
)
RMC-4550 is a potent and selective SHP2 inhibitor.
RGX-104 HCl
(Catalog# : 186234, Cas# :
610318-03-1
)
RGX-104 is a liver X receptor beta agonist with potential immunomodulating and antine
Resminostat HCl
(Catalog# : 185317, Cas# :
1187075-34-8
)
Resminostat HCl is a potent inhibitor of HDAC1/3/6.
Rovazolac
(Catalog# : 185234, Cas# :
1454288-88-0
)
Rovazolac is an anti-inflammatory drug candidate.
Rolapitant free base
(Catalog# : 185152, Cas# :
5552292-08-7
)
Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, se
RO10-5824
(Catalog# : 185141, Cas# :
189744-46-5
)
RO10-5824 is a D4-selective partial agonist. RO10-5824 is a potent candidate for the
Ricasetron
(Catalog# : 184281, Cas# :
117086-68-7
)
Ricasetron, also known as Brl 46470, is antiemetic and axiolytic.
R-IMPP
(Catalog# : 18413, Cas# :
2133832-83-2
)
R-IMPP is an inhibitor of PCSK9 translation.
Rimegepant
(Catalog# : 18441, Cas# :
1289023-67-1
)
Rimegepant, aslo known as BMS-927711, is a potent, selective, competitive and orally
Ritlecitinib ( PF-06651600 )
(Catalog# : 18435, Cas# :
1792180-81-4
)
Ritlecitinib ( PF-06651600 ) is a potent and selective JAK3 inhibitor. PF-06651600, a
R-GNE-140
(Catalog# : 18432, Cas# :
2003234-63-5
)
R-GNE-140 a novel potent lactate dehydrogenase (LDHA) inhibitor with IC50 3nM for LDH
(2R,14R)-4-((R)-1-((R)-4-benzyl-2-oxooxazolidin-3-yl)-3-(tert-butoxycarbonyl)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate
(Catalog# : 183217, Cas# :
2097334-19-3
)
(2R,14R)-4-((R)-1-((R)-4-benzyl-2-oxooxazolidin-3-yl)-3-(tert-butoxycarbonyl)-1-oxopr
(R)-4-(2-(4-benzyl-2-oxooxazolidin-3-yl)-2-oxoethyl)benzyl 2,4-dimethylbenzoate
(Catalog# : 183216, Cas# :
2097334-18-2
)
(R)-4-(2-(4-benzyl-2-oxooxazolidin-3-yl)-2-oxoethyl)benzyl 2,4-dimethylbenzoate is a
Relebactam
(Catalog# : 1712156, Cas# :
1174018-99-5
)
Relebactam,也称为MK- 7655,一个强有力的、具有选择性的β-lactamase抑制
Rimonabant HCl
(Catalog# : 179137, Cas# :
158681-13-1
)
Rimonabant, also known as SR141716, is an anorectic anti-obesity drug. It is an inver
Riviciclib HCl
(Catalog# : 179131, Cas# :
920113-03-7
)
Riviciclib, also known as P276-00 , is a flavone and cyclin dependent kinase (CDK) in
RVT-501
(Catalog# : 17917, Cas# :
947620-48-6
)
RVT-501, also known as E-6005, is a phosphodiesterase 4 (PDE-4) inhibitor potentially
Roluperidone ( CYR-101 )
(Catalog# : 2017889, Cas# :
359625-79-9
)
Roluperidone, also known as MIN-101, CYR-101, and MT-210, is a 5-HT2A and sigma 2 rec
Ranirestat
(Catalog# : 178118, Cas# :
147254-64-6
)
Ranirestat, also known as AS-3201; SX-3201, is an aldose reductase inhibitor being de
RG7800 ( RO6885247 )
(Catalog# : 174192, Cas# :
1449598-06-4
)
RG7800(RO6885247) is a small molecule modifier of survival motor neuron 2 splicing.
Rolapitant HCl
(Catalog# : 17030609, Cas# :
914462-92-3
)
Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, se
RAF709
(Catalog# : 17030605, Cas# :
1628838-42-5
)
RAF709 is a Raf kinase inhibitor.
RPI-1
(Catalog# : 17030301, Cas# :
269730-03-2
)
RPI-1 is an ATP-dependent RET kinase inhibitor. Oral treatment with RPI-1 caused grow
Recilisib sodium
(Catalog# : 17022712, Cas# :
334969-03-8
)
Recilisib, also known as ON 01210.Na, is a radioprotectant, which modifys cell cycle
RO4987655
(Catalog# : 17011603, Cas# :
874101-00-5
)
RO4987655, also known as CH4987655, is an orally active small molecule, targeting mit
Ro 08-2750
(Catalog# : 17011602, Cas# :
37854-59-4
)
Ro 08-2750 is a potent and selective Nerve growth factor (NGF) inhibitor that binds t
Ribociclib HCl
(Catalog# : 17011305, Cas# :
1211443-80-9
)
Ribociclib hydrochloride is an potent and orally available cyclin-dependent kinase (C
Raltitrexed
(Catalog# : 17011303, Cas# :
112887-68-0
)
Raltitrexed, also known as ZD 1694, is an antimetabolite drug used in treatment of co
Retigabine 2HCl
(Catalog# : 17011108, Cas# :
150812-13-8
)
Retigabine is a novel anticonvulsant with activity in a broad range of seizure models
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Vafidemstat
(Catalog# : 18891, Cas# :
1357362-02-7
)
Vafidemstat, also known as ORY 2001, is a lysine-specific histone demethylase (LSD1)
LLL12
(Catalog# : 25075, Cas# :
1260247-42-4
)
LLL12 is a potent STAT3 inhibitor.
ECC-5004
(Catalog# : 26A015, Cas# :
2758659-09-3
)
ECC5004 (AZD5004) is a novel small-molecule GLP-1 RA for use as an oral therapy for c
SILA-123
(Catalog# : 26A014, Cas# :
2911585-37-8
)
SILA-123 is a type II FLT3 inhibitor that has shown highly potent inhibitory effects
Encaleret sulfate
(Catalog# : 26A013, Cas# :
1214922-52-7
)
Encaleret is an investigational small molecule antagonist of the calcium sensing rece
Iadademstat ( ORY-1001 ) hydrochloride
(Catalog# : 26A011, Cas# :
1431303-72-8
)
Iadademstat (ORY-1001) is an orally active, highly potent and selective inhibitor of
DPTX-3186
(Catalog# : 26A010)
DPTX3186, an orally administered small molecule condensate modulator (c-mod) inhibiti
Velzatinib (IDRX-42, M-4205)
(Catalog# : 26A009, Cas# :
2590556-80-0
)
Velzatinib is an orally bioavailable small molecule inhibitor of multiple mutated for
Soficitinib
(Catalog# : 26A008, Cas# :
2574524-67-5
)
Soficitinibis a small-molecule inhibitor of non-receptor tyrosine-protein kinase (TYK
Ofirnoflast
(Catalog# : 26A007, Cas# :
2731294-23-6
)
Ofirnoflast is a first-in-class, orally bioavailable NEK7 inhibitor.