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MAPK
Membrane Transporter/Ion Channel
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Neuronal Signaling
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Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index R
Ritlecitinib tosylate
(Catalog# : 20452, Cas# :
2192215-81-7
)
Ritlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor. PF
Ro 24-7429
(Catalog# : 2320201, Cas# :
139339-45-0
)
Ro24-7429 is a potent and orally activeHIV-1transactivator proteinTatantagonist. Ro24
RP-5063(Brilaroxazine)
(Catalog# : 822224, Cas# :
1239729-06-6
)
RP-5063(Brilaroxazine) is a multimodal modulator of serotonin and dopamine recept
Rucaparib Camsylate
(Catalog# : 20316, Cas# :
1859053-21-6
)
Rucaparib camsylate is a potent, orally available inhibitor of poly ADP-ribose polyme
Rhosin hydrochloride
(Catalog# : 21235, Cas# :
1281870-42-5
)
(R,Z)-1-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino) quinazolin-6-yl)but-2-yn-1-one O-morpholin-3-ylmethyl oxime
(Catalog# : 20123102, Cas# :
1831116-75-6
)
Razuprotafib sodium
(Catalog# : 201221, Cas# :
1809275-69-1
)
Razuprotafib, also known as AKB-9778, is a small molecule inhibitor of vascular endot
Razuprotafib
(Catalog# : 20102901, Cas# :
1008510-37-9
)
Razuprotafib, also known as AKB-9778, is a small molecule inhibitor of vascular endot
Remibrutinib ( LOU064 )
(Catalog# : 2073103, Cas# :
1787294-07-8
)
Remibrutinib ( LOU064 ) is a Potent and Highly Selective Covalent Inhibitor of Bruton
Remdesivir
(Catalog# : 2071545, Cas# :
1809249-37-3
)
Remdesivir, also known as GS-5734, is a prodrug form of the antiviral nucleoside anal
RK-287107
(Catalog# : 2071520, Cas# :
2171386-10-8
)
RK-287107 is a potent TNKS/TNKS2 inhibitor (IC50 = 14.4 nM) with >7000-fold select
RBN-2397
(Catalog# : 207101, Cas# :
2381037-82-5
)
(2R,6S)-tert-butyl 4-(4-aminobenzoyl)-2,6-dimethylpiperazine-1-carboxylate
(Catalog# : 2062334, Cas# :
2161337-98-8
)
(R)-methyl 2-(tert-butyldimethylsilyloxy)propanoate
(Catalog# : 202329, Cas# :
171230-81-2
)
3-[(2RS)-tetrahydro-2H-pyran-2-yloxy]propanoic acid
(Catalog# : 2062017, Cas# :
1221443-23-7
)
((1R,2S)-2-(3-fluorophenyl)-2-(hydroxymethyl)cyclopropyl)methyl acetate
(Catalog# : 2062004, Cas# :
1369768-29-5
)
Rigosertib
(Catalog# : 690120, Cas# :
592542-59-1
)
Rigosertib(ON-01910) is a multi-kinase inhibitor and a selective anti-cancer agent, w
Resatorvid
(Catalog# : 206102, Cas# :
243984-11-4
)
Resatorvid, also known as TAK-242, is a cell-permeable inhibitor of TLR4 signaling, b
RU320521
(Catalog# : 204503, Cas# :
2262452-06-0
)
RU320521, also known as RU521; RU.521 is a potent and selective inhibitor of cGAS, in
(R)-tert-butyl 2-(2-ethynyl-2-methylpyrrolidin-1-yl)acetate
(Catalog# : 580586, Cas# :
2086689-88-3
)
(R)-tert-butyl 2-(2-ethynyl-2-methylpyrrolidin-1-yl)acetate, CAS 2086689-88-3, is a v
Remetinostat
(Catalog# : 193111, Cas# :
946150-57-8
)
Remetinostat, also known as SHP-141, is a topical formulation containing the histone
RG7834
(Catalog# : 19355, Cas# :
2072057-17-9
)
RG7834,also known as RO7020322, is a novel oral HBV viral gene expression inhibitor
RWJ-56110
(Catalog# : 19353, Cas# :
252889-88-6
)
RWJ-56110 is a selective protease-activated receptor-1 (PAR1) antagonist. It blocks t
RBC8
(Catalog# : 19313, Cas# :
361185-42-4
)
RBC8 is a RalA and RalB GTPase inhibitor (EC50 ~3.5 μM). RBC8 suppresses growth of x
Rogaratinib
(Catalog# : 192277, Cas# :
1443530-05-9
)
Rogaratinib, also known as BAY-1163877, is an aberrant fibroblast growth factor recep
Rebimastat
(Catalog# : 192254, Cas# :
259188-38-0
)
Rebimastat, also known as BMS275291, is a sulfhydryl-based second-generation matrix m
Retosiban
(Catalog# : 192193, Cas# :
820957-38-8
)
Retosiban, also known as GSK-221149-A; is an oral active, potent and selective, sub-n
RKI-1313
(Catalog# : 19183, Cas# :
1342276-76-9
)
RKI-1313 Negative control for RKI-1447 (GLXC-05200) which is a potent inhibitor of th
RGX-104 free form
(Catalog# : 19181, Cas# :
610318-54-2
)
RGX-104, also known as SB 742881, is a liver X receptor beta agonist with potential i
R547
(Catalog# : 1811151, Cas# :
741713-40-6
)
R547 is orally bioavailable diaminopyrimidine cyclin-dependent kinase inhibitor (CDKI
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
(Rac)-AF710B
(Catalog# : 24083, Cas# :
1235733-73-9
)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
Flurpiridaz-nonradiolabeled
(Catalog# : 25203, Cas# :
863888-33-9
)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
Flurpiridaz-Precursor
(Catalog# : 25202, Cas# :
863888-32-8
)
Flurpiridaz-Precursor in stock.
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran