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RO4929097

Catalog No.: 123001
Cas No.: 847925-91-1
Purity : 98% 
123001 - RO4929097 | CAS 847925-91-1

Catalog number : 123001

CAS number : 847925-91-1

Molecular Formula : C22H20F5N3O3 

Molecular Weight : 469.405 

Iupac Chemical Name : 2,2-dimethyl-N-[(7S)-6-oxo-5,7-dihydrobenzo[d][1]benzazepin-7-yl]-N'-(2,2,3,3,3-pentafluoropropyl)propanediamide 

Smile : CC(C)(C(=O)NCC(C(F)(F)F)(F)F)C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3NC1=O

InChiKey : OJPLJFIFUQPSJR-UHFFFAOYSA-N

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SynonymsRO-4929097; RO 4929097 
Molecular FormulaC22H20F5N3O3 
Molecular Weight469.405 
AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileCC(C)(C(=O)NCC(C(F)(F)F)(F)F)C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3NC1=O
InChiKeyOJPLJFIFUQPSJR-UHFFFAOYSA-N
InChiInChI=1S/C22H20F5N3O3/c1-20(2,18(32)28-11-21(23,24)22(25,26)27)19(33)30-16-14-9-4-3-7-12(14)13-8-5-6-10-15(13)29-17(16)31/h3-10,16H,11H2,1-2H3,(H,28,32)(H,29,31)(H,30,33)
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RO4929097 is a secretase inhibitor with IC50 of 4 nM, inhibiting cellular processing of A40 and Notch with EC50 of 14 nM and 5 nM, respectively. 

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