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Ritlecitinib ( PF-06651600 )

Catalog No.: 18435
Cas No.: 1792180-81-4
Purity : ≧98.0%

Ritlecitinib ( PF-06651600 )  is a potent and selective JAK3 inhibitor. PF-06651600, a potent and low clearance compound with demonstrated in vivo efficacy.

For research use only. We do not sell to patients.

Chemical Information

NameRitlecitinib ( PF-06651600 )
Iupac Chemical Name1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one
SynonymsPF-06651600 ; PF 06651600 ; PF06651600 ; Ritlecitinib
Molecular FormulaC18H23N5O5
Molecular Weight389.412
SmileC=CC(N1[C@@H](C)CC[C@@H](NC2=C3C(NC=C3)=NC=N2)C1)=O
InChiKeyCBRJPFGIXUFMTM-WDEREUQCSA-N
InChiInChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
CAS Number1792180-81-4
Related CAS1792180-81-4 (free base) 2140301-97-7 (malonate)

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
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FormulationOff-white solid to white solid
Purity≧98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO, not in water
HandlingAvoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation.
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

18435 - Ritlecitinib ( PF-06651600 ) | CAS 1792180-81-4

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