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PF-06651600

Catalog No.: 18435
Cas No.: 1792180-81-4
Purity : >98%
18435 - PF-06651600 | CAS 1792180-81-4

Catalog number : 18435

CAS number : 1792180-81-4

Molecular Formula : C18H23N5O5

Molecular Weight : 389.412

Iupac Chemical Name : 1-[(2S,5R)-2-Methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-2-propen-1-one malonate

Smile : C=CC(N1[C@@H](C)CC[C@@H](NC2=C3C(NC=C3)=NC=N2)C1)=O.O=C(O)CC(O)=O

InChiKey : QMPMPSGDPRHZCG-VZXYPILPSA-N, CBRJPFGIXUFMTM-WDEREUQCSA-N (free base).

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SynonymsPF-06651600; PF 06651600; PF06651600; PF-06651600 malonate.
Molecular FormulaC18H23N5O5
Molecular Weight389.412
AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO, not in water
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
SmileC=CC(N1[C@@H](C)CC[C@@H](NC2=C3C(NC=C3)=NC=N2)C1)=O.O=C(O)CC(O)=O
InChiKeyQMPMPSGDPRHZCG-VZXYPILPSA-N, CBRJPFGIXUFMTM-WDEREUQCSA-N (free base).
InChiInChI=1S/C15H19N5O.C3H4O4/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15;4-2(5)1-3(6)7/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19);1H2,(H,4,5)(H,6,7)/t10-,11+;/m0./s1
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PF-06651600 is a potent and selective JAK3 inhibitor. PF-06651600, a potent and low clearance compound with demonstrated in vivo efficacy.

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