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R547

Catalog No: 1811151
CAS Number: 741713-40-6
Purity: >98%

R547 is orally bioavailable diaminopyrimidine cyclin-dependent kinase inhibitor (CDKI) with potential antineoplastic activity.

For research use only. We do not sell to patients.

Chemical Information

NameR547
Iupac Chemical Name(4-amino-2-((1-(methylsulfonyl)piperidin-4-yl)amino)pyrimidin-5-yl)(2,3-difluoro-6-methoxyphenyl)methanone
SynonymsR547; R 547; R-547; Ro4584820; Ro-4584820; Ro 4584820.
Molecular FormulaC18H21F2N5O4S
Molecular Weight441.45
SmileO=C(C1=CN=C(NC2CCN(S(=O)(C)=O)CC2)N=C1N)C3=C(OC)C=CC(F)=C3F
InChiKeyJRNJNYBQQYBCLE-UHFFFAOYSA-N
InChiInChI=1S/C18H21F2N5O4S/c1-29-13-4-3-12(19)15(20)14(13)16(26)11-9-22-18(24-17(11)21)23-10-5-7-25(8-6-10)30(2,27)28/h3-4,9-10H,5-8H2,1-2H3,(H3,21,22,23,24)
CAS Number741713-40-6
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationOff-white solid to white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

1811151 - R547 | CAS 741713-40-6

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