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MMAD

Catalog No: 20179132
CAS Number: 203849-91-6
Purity: 98.0%

MMAD, also known as Monomethyl auristatin D, is a highly potent Tubulin inhibitor. MMAD is one of the auristatins, which are used as the drugs of antibody drug conjugates(ADCs).

For research use only. We do not sell to patients.

Chemical Information

NameMMAD
Iupac Chemical Name(S)-N-((3R,4S,5S)-3-methoxy-1-((S)-2-((1R,2R)-1-methoxy-2-methyl-3-oxo-3-(((S)-2-phenyl-1-(thiazol-2-yl)ethyl)amino)propyl)pyrrolidin-1-yl)-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide
SynonymsMMAD, Demethyldolastatin 10; Monomethylauristatin D; Monomethyl Dolastatin 10.
Molecular FormulaC41H66N6O6S
Molecular Weight771.075
SmileCO[C@H](CC(=O)N1[C@@H](CCC1)[C@@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C=1SC=CN1)=O)C)OC)[C@H]([C@H](CC)C)N(C([C@H](C(C)C)NC([C@H](C(C)C)NC)=O)=O)C
InChiKeyBLUGYPPOFIHFJS-UUFHNPECSA-N
InChiInChI=1S/C41H66N6O6S/c1-12-27(6)36(46(9)41(51)35(26(4)5)45-39(50)34(42-8)25(2)3)32(52-10)24-33(48)47-21-16-19-31(47)37(53-11)28(7)38(49)44-30(40-43-20-22-54-40)23-29-17-14-13-15-18-29/h13-15,17-18,20,22,25-28,30-32,34-37,42H,12,16,19,21,23-24H2,1-11H3,(H,44,49)(H,45,50)/t27-,28+,30-,31-,32+,34-,35-,36-,37+/m0/s1
CAS Number203849-91-6
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationoff-white solid
Purity98.0%
Storage-20 ℃ for 3 years
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

20179132 - MMAD | CAS 203849-91-6

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