+86-27-65522453 sales@sun-shinechem.com

MI-503

Catalog No.: 178908
Cas No.: 1857417-13-0
Purity : 98.0% 
178908 - MI-503 | CAS 1857417-13-0

Catalog number : 178908

CAS number : 1857417-13-0

Molecular Formula : C28H27F3N8S 

Molecular Weight : 564.64 

Iupac Chemical Name : 4-Methyl-1-(1H-pyrazol-4-ylmethyl)-5-[[4-[[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-1H-indole-2-carbonitrile 

Smile : CC1=C2C=C(N(C2=CC=C1CN1CCC(CC1)NC=1C2=C(N=CN1)SC(=C2)CC(F)(F)F)CC=2C=NNC2)C#N

InChiKey : DETOMBLLEOZTMZ-UHFFFAOYSA-N

PackagingPriceAvailabilityPurityEstimated Shipping Time
BulkEnquiryEnquiry
Request Bulk Quote Download MSDSTel:+86-27-65522453 | Email:sales@sun-shinechem.com
SynonymsMI503 
Molecular FormulaC28H27F3N8S 
Molecular Weight564.64 
Appearanceoff-white solid 
Purity98.0% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileCC1=C2C=C(N(C2=CC=C1CN1CCC(CC1)NC=1C2=C(N=CN1)SC(=C2)CC(F)(F)F)CC=2C=NNC2)C#N
InChiKeyDETOMBLLEOZTMZ-UHFFFAOYSA-N
InChiInChI=1S/C28H27F3N8S/c1-17-19(2-3-25-23(17)8-21(11-32)39(25)14-18-12-35-36-13-18)15-38-6-4-20(5-7-38)37-26-24-9-22(10-28(29,30)31)40-27(24)34-16-33-26/h2-3,8-9,12-13,16,20H,4-7,10,14-15H2,1H3,(H,35,36)(H,33,34,37)
Coming soon.
MI-503 is a potent and selective Menin-MLL inhibitor with IC50 of 14.7 nM. It shows pronounced growth suppressive activity in a panel of human MLL leukemia cell lines(GI50 at 250 nM-570 nM range). 

1857417-13-0 - Request Bulk Quote

×
1857417-13-0 - Request Bulk Quote
Change