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ML-277

Catalog No.: 179115
Cas No.: 516480-79-8
Purity : 98.0%
179115 - ML-277 | CAS 516480-79-8

Catalog number : 179115

CAS number : 516480-79-8

Molecular Formula : C20H14ClN3O2

Molecular Weight : 363.8

Iupac Chemical Name : 2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide

Smile : ClC1=CC=C(OC2=CC=C(C=C2)C2=NC3=C(N2)C=CC(=C3)C(=O)N)C=C1

InChiKey : UXGJAOIJSROTTN-UHFFFAOYSA-N

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SynonymsML-277; ML 277; ML277; Chk2 Inhibitor II.
Molecular FormulaC20H14ClN3O2
Molecular Weight363.8
Appearanceoff-white solid
Purity98.0%
SolubilitySoluble in DMSO
Storage-20 ℃ for 3 years
Shipping ConditionShipped under ambient temperature
SmileClC1=CC=C(OC2=CC=C(C=C2)C2=NC3=C(N2)C=CC(=C3)C(=O)N)C=C1
InChiKeyUXGJAOIJSROTTN-UHFFFAOYSA-N
InChiInChI=1S/C20H14ClN3O2/c21-14-4-8-16(9-5-14)26-15-6-1-12(2-7-15)20-23-17-10-3-13(19(22)25)11-18(17)24-20/h1-11H,(H2,22,25)(H,23,24)
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ML-277, also known as Chk2 Inhibitor II, is a Chk2 (checkpoint kinase 2) inhibitor. BML-277 protects T cells from apoptosis by controlling the response of p53 to radiation-induced DNA breaks.

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