ML-385
Catalog No: 179119
CAS Number: 846557-71-9
Purity: 98.0%
ML-385 is a potent and selective NRF2 inhibitor (Nrf2; IC50 = 1.9 μM) . ML-385 selectively intervenes therapeutic resistance in KEAP1-Deficient NSCLC Tumors.
For research use only. We do not sell to patients.
Chemical Information
| Name | ML-385 |
|---|---|
| Iupac Chemical Name | N-[4-[2,3-dihydro-1-(2-methylbenzoyl)-1H-indol-5-yl]-5-methyl-2-thiazolyl]-1,3-benzodioxole-5-acetamide |
| Synonyms | ML-385; ML 385; ML385. |
| Molecular Formula | C29H25N3O4S |
| Molecular Weight | 511.596 |
| Smile | CC1=C(C(=O)N2CCC3=CC(=CC=C23)C=2N=C(SC2C)NC(CC2=CC3=C(OCO3)C=C2)=O)C=CC=C1 |
| InChiKey | LINHYWKZVCNAMQ-UHFFFAOYSA-N |
| InChi | InChI=1S/C29H25N3O4S/c1-17-5-3-4-6-22(17)28(34)32-12-11-20-15-21(8-9-23(20)32)27-18(2)37-29(31-27)30-26(33)14-19-7-10-24-25(13-19)36-16-35-24/h3-10,13,15H,11-12,14,16H2,1-2H3,(H,30,31,33) |
| CAS Number | 846557-71-9 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98.0% |
| Storage | -20 ℃ for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
