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Immunology & Inflammation
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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
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Name Index L
LJI308
(Catalog# : 16070904, Cas# :
1627709-94-7
)
LJI308 is a potent, and pan-RSK(p90 ribosomal S6 kinase) inhibitor withIC50of 6 nM, 4
LJH685
(Catalog# : 16070903, Cas# :
1627710-50-2
)
LJH685 is a potent pan-RSKinhibitor withIC50of 6 nM, 5 nM and 4 nM for RSK1, RSK2, an
LX1606 (Hippurate)
(Catalog# : 16062301, Cas# :
1137608-69-5
)
LX1606 is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibi
Lumateperone(ITI-007)
(Catalog# : 632801, Cas# :
313368-91-1
)
ITI-007 is an investigational atypical antipsychotic which is currently under develop
LGD-4033(Ligandrol)
(Catalog# : 030907, Cas# :
1165910-22-4
)
LGD-4033, also known as VK5211 and Ligandrol, is an investigational selective androge
LY-379268
(Catalog# : 011904, Cas# :
191471-52-0
)
Coming soon!
Lefamulin acetate
(Catalog# : 011808, Cas# :
1350636-82-6
)
Coming soon!
Lefamulin
(Catalog# : 011807, Cas# :
1061337-51-6
)
Coming soon!
L-165041
(Catalog# : 011316, Cas# :
79558-09-1
)
Coming soon!
Linsitinib
(Catalog# : 010819, Cas# :
867160-71-2
)
Linsitinib is highly potent, orally efficacious and highly selective, dual ATP-compet
Lestaurtinib
(Catalog# : 010815, Cas# :
111358-88-4
)
Lesraurtinib is an orally bioavailable indolocarbazole derivative with antineoplastic
LX7101
(Catalog# : 010802, Cas# :
1192189-69-7
)
LX7101 is a potent inhibitor of LIMK1/2, ROCK2 and PKA, with IC50 of 24/1.6, 10, and
Loratadine
(Catalog# : 010435, Cas# :
79794-75-5
)
Loratadine is a selective inverse peripheral histamine H1-receptor agonist with an IC
LY2584702 free base
(Catalog# : 122909, Cas# :
1082949-67-4
)
LY2584702 is an orally available inhibitor of p70S6K signaling; inhibits p70S6K and p
LY2584702 tosylate
(Catalog# : 122907, Cas# :
1082949-68-5
)
LY-2584702 tosylate salt is an orally available inhibitor of p70S6K signaling; inhibi
L-779450
(Catalog# : 122835, Cas# :
303727-31-3
)
L-779450 is a potent, selective and ATP-competitive Raf kinase inhibitor (IC50 = 10 n
LDN193189 Hydrochloride
(Catalog# : 122830, Cas# :
1062368-62-0
)
LDN193189 Hydrochloride is a selective BMP signaling inhibitor, inhibits the transcri
LCL161
(Catalog# : 122820, Cas# :
1005342-46-0
)
LCL161 is an orally bioavailable SMAC mimetic and inhibitor of Inhibitor of Apoptosis
Lexibulin
(Catalog# : 122803, Cas# :
917111-44-5
)
Lexibulin is an orally bioavailable small-molecule with tubulin-inhibiting, vascular-
LY2228820
(Catalog# : 122509, Cas# :
862507-23-1
)
LY2228820 is a novel and potent p38MAPK inhibitor (the IC50 for p38MAPK and p38MAPK w
LY2608204
(Catalog# : 122218, Cas# :
1234703-40-2
)
LY2608204 is a activator of glucokinase (GK) with EC50 of 42 nM.
L-778123 hydrochloride
(Catalog# : 121805, Cas# :
253863-00-2
)
L-778123 hydrochloride is an inhibitor of FPTase and GGPTase-I with IC50 of 2 nM and
Laquinimod
(Catalog# : 121506, Cas# :
248281-84-7
)
Laquinimod is an experimental immunomodulator developed by Active Biotech and Teva.
LY2811376
(Catalog# : 121435, Cas# :
1194044-20-6
)
LY2811376 is a BACE1 inhibitor with marked Ab-lowering effects in animal models.
LY2886721
(Catalog# : 121427, Cas# :
1262036-50-9
)
LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease.
Linifanib
(Catalog# : 121416, Cas# :
796967-16-3
)
Linifanib is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR, CSF-1R, F
LY2090314
(Catalog# : 5121102, Cas# :
603288-22-8
)
LY2090314 (LY) is a glycogen synthase kinase 3 inhibitor with preclinical efficacy in
LMK 235
(Catalog# : 120422, Cas# :
1418033-25-6
)
LMK 235 is a selective histone deacetylase (HDAC) 4 and HDAC5 inhibitor, which demons
LDN-57444
(Catalog# : 110606, Cas# :
668467-91-2
)
LDN-57444 is a Uch-L1 inhibitor with Ki= 0.4 M. Ubiquitin carboxy-terminal hydrolase
Leuprolide
(Catalog# : 110603, Cas# :
53714-56-0
)
Leuprolide is an agonist at pituitary GnRH receptors.
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Ranosidenib
(Catalog# : 25150, Cas# :
2301974-60-5
)
Ranosidenib, also known as HMPL-306, is an isocitrate dehydrogenase (IDH) inhibitor.
AZD0095
(Catalog# : 237072, Cas# :
2750001-23-9
)
AZD0095 is a Selective Inhibitor of Monocarboxylate Transporter 4 (MCT4) for Oncology.
2-MNG
(Catalog# : 24129, Cas# :
2101538-28-5
)
2-MNG is a new potent melanogenesis inhibitor, which exhibits a unique mode of action
MAT2A-IN-9
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 (compound 167), a 2-oxoquinazoline derivative, is a potent MAT2A (methioni
Safusidenib
(Catalog# : 25149, Cas# :
1898206-17-1
)
Safusidenib, also known as DS-1001, is an oral isocitrate dehydrogenase [NADP] cytopl
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1
Acoramidis hydrochloride
(Catalog# : 24068, Cas# :
2242751-53-5
)
Acoramidis is an oral, potent, and highly selective small molecule transthyretin (TTR
Crelosidenib
(Catalog# : 24101, Cas# :
2230263-60-0
)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor.
LOXO-435
(Catalog# : 25080, Cas# :
2833703-74-3
)
LOXO-435 is a selective small molecule inhibitor of FGFR3. It is active against both
Gridegalutamide
(Catalog# : 25138, Cas# :
2446928-30-7
)
Gridegalutamide, also known as BMS-986365 and CC-94676, is a heterobifunctional, firs