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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
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Name Index L
LY2881835
(Catalog# : 185252, Cas# :
1292290-38-0
)
LY2881835 is a potent and selective GPR40 agonist potentially for treatment of type 2
LOXO-195
(Catalog# : 185212, Cas# :
2097002-61-2
)
LOXO-195 is a potent and selective TRK inhibitor capable of addressing potential mech
Lanifibranor
(Catalog# : 184177, Cas# :
927961-18-0
)
Lanifibranor, also known as IVA-337, is a peroxisome proliferator-activated receptors
LX-2343
(Catalog# : 184131, Cas# :
333745-53-2
)
LX-2343 is a neuroprotective agent for the treatment of Alzheimer's disease.
Lazertinib
(Catalog# : 512194, Cas# :
1903008-80-9
)
Description:Lazertinib is a an orally available third-generation, selective inhibi
LYN-1604
(Catalog# : 18493, Cas# :
2088939-99-3
)
LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, a
LB42708
(Catalog# : 18443, Cas# :
226929-39-1
)
LB42708 is a potent, orally active and selective nonpeptidic farnesyltransferase inhi
LLY-283
(Catalog# : 184314, Cas# :
2040291-27-6
)
LLY-283 is a potent and selective SAM-competitive chemical probe for PRMT5.
L-778123
(Catalog# : 1711249, Cas# :
183499-57-2
)
L-778,123 is an inhibitor of FPTase and GGPTase-I.
LW6
(Catalog# : 17101618, Cas# :
934593-90-5
)
LW6 decreased HIF-1alpha protein expression without affecting HIF-1beta expression.
LF3
(Catalog# : 1710164, Cas# :
664969-54-4
)
LF3 is a specific inhibitor of the classical Wnt signaling pathway by disrupting the
LTURM-34
(Catalog# : 1710138, Cas# :
1879887-96-3
)
LTURM-34 is a novel potent and selective DNA-PK inhibitor, attenuating proliferation
LY2606368 dihydrochloride
(Catalog# : 1710137, Cas# :
1234015-54-3
)
Prexasertib (LY2606368) is an ATP-competitive CHK1 inhibitor with a Ki value of 0.9 n
LDC1267
(Catalog# : 179301, Cas# :
1361030-48-9
)
LDC1267 markedly reduced murine mammary cancer and melanoma metastases dependent on N
Lavendustin C
(Catalog# : 1791119, Cas# :
125697-93-0
)
Lavendustin C, also known as HDBA and NSC 666251, is a potent inhibitor of epidermal
Lenvatinib (E7080)
(Catalog# : 52025, Cas# :
417716-92-8
)
Lenvatinib, also known as E7080, is a synthetic, orally available inhibitor of vascul
LXS-196
(Catalog# : 1781108, Cas# :
1874276-76-2
)
<span style="color:#34495E;font-family:"font-size:14px;background-color:
LDC4297(LDC044297)
(Catalog# : 178902, Cas# :
1453834-21-3
)
LDC4297,also known as LCD044297,is a potent and selective CDK7 inhibitor.
LY3214996
(Catalog# : 2017887, Cas# :
1951483-29-6
)
LY-3214996 is a potent and selective, orally available inhibitor of extracellular sig
LTX-315
(Catalog# : 20178218, Cas# :
1345407-05-7
)
LTX-315 is an amphipathic cationic peptide potentially for the treatment of melanoma,
LY 344864
(Catalog# : 20178212, Cas# :
186544-26-3
)
LY344864 is a selective 5-HT1F receptor agonist with an affinity of 6 nM (Ki) at the
LY 344864 hydrochloride
(Catalog# : 2017828, Cas# :
1217756-94-9
)
LY344864 hydrochloride is a potent and selective 5-HT1F receptor agonist. It has an E
Lys05 trihydrochloride
(Catalog# : 17030102, Cas# :
1391426-24-6
)
Lys05, or Lys01 trihydrochloride, is a potent, water soluble lysosomal autophagy inhi
Lapatinib
(Catalog# : 17022807, Cas# :
231277-92-2
)
Lapatinib(GW-572016) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 n
Lesinurad
(Catalog# : 17022706, Cas# :
878672-00-5
)
Lesinurad(RDEA594), once-daily inhibitor of URAT1, is a transporter in the kidney tha
LY3039478 ( Crenigacestat )
(Catalog# : 17021601, Cas# :
1421438-81-4
)
LY3039478 ( Crenigacestat ), a selective NOTCH1 inhibitor, reduces intrahepatic chola
LCI699
(Catalog# : 17021314, Cas# :
928134-65-0
)
LCI699(Osilodrostat) is a potent inhibitor of 11-hydroxylase, an enzyme catalyzing t
lumateperone(Tosylate)
(Catalog# : 17012102, Cas# :
1187020-80-9
)
Lumateperone (ITI-722/ITI-007) is a novel, first-in-class dual 5HT2A receptor antagon
Lys05
(Catalog# : 16123043, Cas# :
1391426-22-4
)
Lys05 is a potent lysosomal autophagy inhibitor. Lys05 is a previously undescribed di
LY-3177833
(Catalog# : 16123042, Cas# :
1627696-51-8
)
LY-3177833 is a potent and selective inhibitor of CDC7 (Cell Division Cycle 7-related
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1
Acoramidis hydrochloride
(Catalog# : 24068, Cas# :
2242751-53-5
)
Acoramidis is an oral, potent, and highly selective small molecule transthyretin (TTR
Crelosidenib
(Catalog# : 24101, Cas# :
2230263-60-0
)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor.
LOXO-435
(Catalog# : 25080, Cas# :
2833703-74-3
)
LOXO-435 is a selective small molecule inhibitor of FGFR3. It is active against both
MAT2A-IN-9
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 (compound 167), a 2-oxoquinazoline derivative, is a potent MAT2A (methioni
Gridegalutamide
(Catalog# : 25138, Cas# :
2446928-30-7
)
Gridegalutamide, also known as BMS-986365 and CC-94676, is a heterobifunctional, firs
Chiauranib
(Catalog# : 25146, Cas# :
1256349-48-0
)
Chiauranib also known as orally available, small molecule inhibitor of select serine-
Atuzabrutinib
(Catalog# : 25145, Cas# :
1581714-49-9
)
Atuzabrutinib, also known as PRN 473, is a Bruton's tyrosine kinase inhibitor.
Andamertinib
(Catalog# : 25144, Cas# :
2254145-43-0
)
Andamertinib is an epidermal growth factor receptor tyrosine kinase inhibitor. It is
MEN-1703
(Catalog# : 25143, Cas# :
2769008-22-0
)