Irafamdastat (Synonyms: BMS-986368)
Catalog No: 25154
CAS Number: 2244136-58-9
Purity: ≧98.0%
Irafamdastat (BMS-986368; formerly known as ABX-1772) is an oral, CNS-penetrant, small-molecule inhibitor of the fatty acid amide hydrolase (FAAH) and the monoglyceride lipase (MGLL) enzymes.
For research use only. We do not sell to patients.
Chemical Information
| Name | Irafamdastat (Synonyms: BMS-986368) |
|---|---|
| Iupac Chemical Name | 5-Carbamoylpyridin-3-yl (2R)-2-methyl-4-[[3-(trifluoromethoxy)phenyl]methyl]piperazine-1-carboxylate |
| Synonyms | ABD-115672 ; ABX-1772 ; BMS-986368 ; CC-97489 |
| Molecular Formula | C20H21F3N4O4 |
| Molecular Weight | 438.41 |
| Smile | O=C(N1[C@H](C)CN(CC2=CC=CC(OC(F)(F)F)=C2)CC1)OC3=CC(C(N)=O)=CN=C3 |
| InChiKey | XXDVCULQMDDOAX-CYBMUJFWSA-N |
| InChi | InChI=1S/C20H21F3N4O4/c1-13-11-26(12-14-3-2-4-16(7-14)31-20(21,22)23)5-6-27(13)19(29)30-17-8-15(18(24)28)9-25-10-17/h2-4,7-10,13H,5-6,11-12H2,1H3,(H2,24,28)/t13-/m1/s1 |
| CAS Number | 2244136-58-9 |
| Related CAS | 2244136-58-9 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | FAAH Inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study | phase II clinical development stage |
Not available
Chemical Structure
