Irpagratinib
Catalog No: 25089
CAS Number: 2230974-62-4
Purity: ≧98.0%
Irpagratinib is an orally bioavailable, selective inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity.
For research use only. We do not sell to patients.
Chemical Information
| Name | Irpagratinib |
|---|---|
| Iupac Chemical Name | N-[(3S,4S)-3-{[6-(2,6-difluoro-3,5-dimethoxyphenyl)-8-(3-methoxy-3-methylazetidin-1-yl)pyrido[3,4-d]pyrimidin-2-yl]amino}oxan-4-yl]prop-2-enamide |
| Synonyms | Irpagratinib; ABSK011; ABSK-011; ABSK 011 |
| Molecular Formula | C28H32F2N6O5 |
| Molecular Weight | 570.59 |
| Smile | C=CC(N[C@@H]1[C@H](NC2=NC=C3C(C(N4CC(C)(OC)C4)=NC(C5=C(F)C(OC)=CC(OC)=C5F)=C3)=N2)COCC1)=O |
| InChiKey | PGRHEHZIRYNZDV-FUHWJXTLSA-N |
| InChi | InChI=1S/C28H32F2N6O5/c1-6-21(37)32-16-7-8-41-12-18(16)34-27-31-11-15-9-17(22-23(29)19(38-3)10-20(39-4)24(22)30)33-26(25(15)35-27)36-13-28(2,14-36)40-5/h6,9-11,16,18H,1,7-8,12-14H2,2-5H3,(H,32,37)(H,31,34,35)/t16-,18+/m0/s1 |
| CAS Number | 2230974-62-4 |
| Related CAS | 2230974-62-4 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
