Inupadenant
Catalog No: 24138
CAS Number: 2246607-08-7
Purity: 98% Min.
Inupadenant, also known as EOS-850, is a highly selective small molecule antagonist of the adenosine A2a receptor, in the adenosine triphosphate adenosine pathway, a key driver of immunosuppression in the tumor microenvironment across a broad range of tumors.
For research use only. We do not sell to patients.
Chemical Information
| Name | Inupadenant |
|---|---|
| Iupac Chemical Name | (+)-5-amino-3-{2-[4-(2,4-difluoro-5-{2-[(S)-methanesulfinyl]ethoxy}phenyl)piperazin-1-yl]ethyl}-8-(furan-2-yl)[1,3]thiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidin-2(3H)-one |
| Synonyms | Inupadenant; EOS 100850; EOS100850; EOS-100850; EOS-850; EOS 850; EOS850; |
| Molecular Formula | C25H26F2N8O4S2 |
| Molecular Weight | 604.65 |
| Smile | O=C(N1CCN2CCN(C3=CC(OCC[S@](C)=O)=C(F)C=C3F)CC2)SC4=C1N=C(N)N5C4=NC(C6=CC=CO6)=N5 |
| InChiKey | QYCCLUSYHJXDEX-RWYGWLOXSA-N |
| InChi | InChI=1S/C25H26F2N8O4S2/c1-41(37)12-11-39-19-14-17(15(26)13-16(19)27)33-7-4-32(5-8-33)6-9-34-22-20(40-25(34)36)23-29-21(18-3-2-10-38-18)31-35(23)24(28)30-22/h2-3,10,13-14H,4-9,11-12H2,1H3,(H2,28,30)/t41-/m0/s1 |
| CAS Number | 2246607-08-7 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
