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GNE-6640

Catalog No.: 1812291
Cas No.: 2009273-67-8
Purity : >98%
1812291 - GNE-6640 | CAS 2009273-67-8

Catalog number : 1812291

CAS number : 2009273-67-8

Molecular Formula : C20H18N4O

Molecular Weight : 330.39

Iupac Chemical Name : 4-[2-Amino-4-ethyl-5-(1H-indazol-5-yl)-3-pyridyl]phenol

Smile : OC1=CC=C(C2=C(CC)C(C3=CC4=C(NN=C4)C=C3)=CN=C2N)C=C1

InChiKey : ZHYXJQQBKROZDX-UHFFFAOYSA-N

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SynonymsGNE-6640; GNE 6640; GNE6640
Molecular FormulaC20H18N4O
Molecular Weight330.39
AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
SmileOC1=CC=C(C2=C(CC)C(C3=CC4=C(NN=C4)C=C3)=CN=C2N)C=C1
InChiKeyZHYXJQQBKROZDX-UHFFFAOYSA-N
InChiInChI=1S/C20H18N4O/c1-2-16-17(13-5-8-18-14(9-13)10-23-24-18)11-22-20(21)19(16)12-3-6-15(25)7-4-12/h3-11,25H,2H2,1H3,(H2,21,22)(H,23,24)
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GNE-6640 is a novel selective USP7 inhibitor, inducing tumor cell death. GNE-6640 enhances cytotoxicity with chemotherapeutic agents and targeted compounds, including PIM kinase inhibitors.

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